Publications of the Week Improving the Secretion of Designed Protein Assemblies Through Negative Design of Cryptic Transmembrane Domains Wang, J.Y.J., et al. | March 15, 2023 Computationally designed protein nanoparticles have recently emerged as a promising platform for the development of…sciencecityMarch 15, 2023 Read More
Publications of the Week A Chemically Controlled Cas9 Switch Enables Temporal Modulation of Diverse Effectors Wei, C.T., et al. | March 14, 2023 CRISPR-Cas9 has yielded a plethora of effectors, including targeted transcriptional activators, base editors and prime…sciencecityMarch 14, 2023 Read More
Publications of the Week Linking Connectome with Transcriptome Using a Self-Inactivating Rabies Virus Yao, S. and Levi, B.P. | March 8, 2023 Genetically engineered rabies virus is a powerful tool for investigating the structure and function of…sciencecityMarch 8, 2023 Read More
Publications of the Week Automatic and Accurate Ligand Structure Determination Guided by Cryo-Electron Microscopy Maps Muenks, A., et al. | March 6, 2023 Advances in cryo-electron microscopy (cryoEM) and deep-learning guided protein structure prediction have expedited structural studies…sciencecityMarch 6, 2023 Read More
Publications of the Week Reversible Epigenetic Alterations Mediate PSMA Expression Heterogeneity in Advanced Metastatic Prostate Cancer Sayer, E., et al. | March 1, 2023 Prostate-specific membrane antigen (PSMA) is an important cell surface target in prostate cancer. There are…pthomsonMarch 1, 2023 Read More
Publications of the Week MUC5AC Genetic Variation Is Associated with Tuberculous Meningitis CSF Cytokine Responses and Mortality Sabo, M. C., et al. | February 28, 2023 Independent SNPs in MUC5B and MUC5AC (genotyped by Illumina HumanOmniExpress array) were assessed for associations with TNF concentrations (measured…pthomsonFebruary 28, 2023 Read More
Publications of the Week ATP Is a Major Determinant of Phototrophic Bacterial Longevity in Growth Arrest Yin, L., et al. | February 22, 2023 How bacteria transition into growth arrest as part of stationary phase has been well-studied, but…sciencecityFebruary 22, 2023 Read More
Publications of the Week Cross-Protective Antibodies against Common Endemic Respiratory Viruses Cabán, M., et al. | February 21, 2023 Respiratory syncytial virus (RSV), human metapneumovirus (HMPV), and human parainfluenza virus types one (HPIV1) and…sciencecityFebruary 21, 2023 Read More
Publications of the Week Anti-HLA Antibodies in Recipients of CD19 versus BCMA-Targeted Car T-Cell Therapy Hill, J.A., et al. | February 15, 2023 Antibodies against foreign human leukocyte antigen (HLA) molecules are barriers to successful organ transplantation. B…sciencecityFebruary 15, 2023 Read More
Publications of the Week A Virus-Packageable CRISPR System Identifies Host Dependency Factors Co-Opted by Multiple HIV-1 Strains Montoya, V.R., et al. | February 14, 2023 At each stage of the HIV life cycle, host cellular proteins are hijacked by the…sciencecityFebruary 14, 2023 Read More