Publications of the Week The Endophilin Curvature-Sensitive Motif Requires Electrostatic Guidance to Recycle Synaptic Vesicles In Vivo Zhang, L., et al. | March 24, 2022 Curvature-sensing mechanisms assist proteins in executing particular actions on various membrane organelles. Here, we investigate…dcorriganMarch 24, 2022 Read More
Publications of the Week Lamin B1 Deletion in Myeloid Neoplasms Causes Nuclear Anomaly and Altered Hematopoietic Stem Cell Function Reilly, A., et al. | March 22, 2022 Abnormal nuclear morphology is a hallmark of most cancers, widely used in cancer diagnosis. In…dcorriganMarch 22, 2022 Read More
Publications of the Week The Alzheimer’s Gene SORL1 Is a Regulator of Endosomal Traffic and Recycling in Human Neurons Mishra, S., et al. | March 16, 2022 In this work, we continued our studies on the gene SORL1, which is emerging as…dcorriganMarch 16, 2022 Read More
Publications of the Week Mechanical Forces Govern Interactions of Host Cells with Intracellular Bacterial Pathogens Bastounis, E. E., et al. | March 16, 2022 To combat infectious diseases, it is important to understand how host cells interact with bacterial…dcorriganMarch 16, 2022 Read More
Publications of the Week REL and BHLHE40 Variants Are Associated with IL-12 and IL-10 Responses and Tuberculosis Risk Journal of Immunology | March 11, 2022 The major human genes regulating Mycobacterium tuberculosis–induced immune responses and tuberculosis (TB) susceptibility are poorly understood.…dcorriganMarch 11, 2022 Read More
Publications of the Week Global and Context-Specific Transcriptional Consequences of Oncogenic Fbw7 Mutations Nayanga Thirmanne, H., et al. | March 9, 2022 The Fbw7 ubiquitin ligase targets many proteins for proteasomal degradation, which include oncogenic transcription factors…dcorriganMarch 9, 2022 Read More
Publications of the Week Cryo-ET of Env on Intact HIV Virions Reveals Structural Variation and Positioning on the Gag Lattice Mangala Prasad, V., et al. | March 4, 2022 HIV-1 Env mediates viral entry into host cells and is the sole target for neutralizing…dcorriganMarch 4, 2022 Read More
Publications of the Week MBNL1 Drives Dynamic Transitions between Fibroblasts and Myofibroblasts in Cardiac Wound Healing Bugg, D., et al. | March 2, 2022 Dynamic fibroblast to myofibroblast state transitions underlie the heart’s fibrotic response. Because transcriptome maturation by…dcorriganMarch 2, 2022 Read More
Publications of the Week Genetic Dissection of Antibiotic Adjuvant Activity Bailey, J., et al. | February 25, 2022 Small molecule adjuvants that enhance the activity of established antibiotics represent promising agents in the…dcorriganFebruary 25, 2022 Read More
Publications of the Week Defining Molecular Glues with a Dual-Nanobody Cannabidiol Sensor Cao, S., et al. | February 22, 2022 “Molecular glue” (MG) is a term coined to describe the mechanism of action of the…dcorriganFebruary 22, 2022 Read More