Publications of the Week Chemokines, Soluble PD-L1, and Immune Cell Hyporesponsiveness are Distinct Features of SARS-CoV-2 Critical Illness Morrell, E. D., et al. | June 16, 2022 Critically ill patients manifest many of the same immune features seen in COVID-19, including both…dcorriganJune 16, 2022 Read More
Publications of the Week TNF-α/IFN-γ Synergy Amplifies Senescence-Associated Inflammation and SARS-CoV-2 Receptor Expression via Hyper-Activated JAK/STAT1 Kandhaya-Pillai, R., et al. | June 10, 2022 Older age and underlying conditions such as diabetes/obesity or immunosuppression are leading host risk factors…pthomsonJune 10, 2022 Read More
Publications of the Week Genome-Wide Protein–DNA Interaction Site Mapping in Bacteria Using a Double-Stranded DNA-Specific Cytosine Deaminase Gallagher, L. A., et al. | June 7, 2022 DNA–protein interactions are central to fundamental cellular processes, yet widely implemented technologies for measuring these…pthomsonJune 7, 2022 Read More
Publications of the Week Thymidine Starvation Promotes C-Di-AMP-Dependent Inflammation during Pathogenic Bacterial Infection Tang, Q., et al. | June 2, 2022 Antimicrobials can impact bacterial physiology and host immunity with negative treatment outcomes. Extensive exposure to…dcorriganJune 2, 2022 Read More
Publications of the Week Impact of CD19 CAR T Cell Product Type on Outcomes in Relapsed or Refractory Aggressive B-NHL Gauthier, J., et al. | June 1, 2022 CD19-targeted chimeric antigen receptor-engineered (CD19 CAR) T cells are novel therapies showing great promise for…dcorriganJune 1, 2022 Read More
Publications of the Week Upregulation of Mitochondrial ATPase Inhibitory Factor 1 (ATPIF1) Mediates Increased Glycolysis in Mouse Hearts Zhou, B., et al. | May 26, 2022 The CDC estimates 6.2 million adults in the US have heart failure, which is a…dcorriganMay 26, 2022 Read More
Publications of the Week Synthetic Lethal Kinases in Ras/p53 Mutant Squamous Cell Carcinoma Moser, R., et al. | May 23, 2022 The authors use patient-derived tumor cells to identify and validate new drug targets as well…dcorriganMay 23, 2022 Read More
Publications of the Week Modified Manufacturing Process Modulates CD19 CAR T Cell Engraftment Fitness and Leukemia-Free Survival in Pediatric and Young Adult Subjects Ceppi, F., et al. | May 20, 2022 T cells modified to express a chimeric-antigen receptor (CAR)targeting CD19 can induce potent and sustained…dcorriganMay 20, 2022 Read More
Publications of the Week A Recombinant Alpha-Like Protein Subunit Vaccine (GBS-NN) Provides Protection in Murine Models of Group B Streptococcus Infection Get Access Arrow Brokaw, A., et al. | May 19, 2022 Group B Streptococcus (GBS) transmission during pregnancy causes preterm labor, stillbirths, fetal injury, or neonatal infections.…dcorriganMay 19, 2022 Read More
Publications of the Week Extricating Human Tumor Immune Alterations from Tissue Inflammation Nature | May 16, 2022 The authors compared human tumor tissues to non-malignant, inflamed tissues and observed extensive phenotypic and…dcorriganMay 16, 2022 Read More