Publications of the Week Mechanical Competition Triggered by Innate Immune Signaling Drives the Collective Extrusion of Bacterially Infected Epithelial CellsBastounis, E. E., et al. | March 8, 2021Intracellular pathogens alter their host cells' mechanics to promote dissemination through tissues. Conversely, host cells…kchenMarch 8, 2021 Read More
Publications of the Week Compartmentalization of Phosphatidylinositol 4,5-Bisphosphate Metabolism Into Plasma Membrane Liquid-Ordered/Raft DomainsMyeong, J., et al. | March 5, 2021Lipids of bilayer membranes can segregate laterally into distinct liquid phases of different composition called…kchenMarch 5, 2021 Read More
Publications of the Week Haplotype-Resolved Diverse Human Genomes and Integrated Analysis of Structural VariationEbert, P., et al. | March 4, 2021Long-read and strand-specific sequencing technologies together facilitate the de novo assembly of high-quality haplotype-resolved human…kchenMarch 4, 2021 Read More
Publications of the Week Cx43 Phosphorylation Sites Regulate Pancreatic Cancer MetastasisSolan, J.L., et al. | March 4, 2021The work discussed here highlights our work on gap junctions. Gap junctions are highly organized…kchenMarch 4, 2021 Read More
Publications of the Week Brain Capillary Pericytes Exert a Substantial but Slow Influence on Blood FlowHartmann, D.A., et al. | February 26, 2021The research in our lab focuses on the smallest blood vessels that deliver oxygen and…kchenFebruary 26, 2021 Read More
Publications of the Week The Krüppel-Like Factor Cabut Has Cell Cycle Regulatory Properties Similar to E2F1Zhang, P., et al. | February 24, 2021Using a gain-of-function screen in Drosophila, we identified the Krüppel-like factor Cabut (Cbt) as a…kchenFebruary 24, 2021 Read More
Publications of the Week Targeting the Membrane-Proximal C2-Set Domain of CD33 for Improved CD33-Directed ImmunotherapyGodwin, C.D., et al. | February 22, 2021There is increasing interest in targeting CD33 in malignant and non-malignant disorders. In acute myeloid…kchenFebruary 22, 2021 Read More
Publications of the Week BRCA1/BARD1 Site-Specific Ubiquitylation of Nucleosomal H2A Is Directed by BARD1Witus, S.R., et al. | February 19, 2021Mutations in the E3 ubiquitin ligase RING domains of BRCA1/BARD1 predispose carriers to breast and…kchenFebruary 19, 2021 Read More
Publications of the Week A Curious Case for Development of Kinase Inhibitors as Antigiardiasis Treatments Using Advanced Drug TechniquesMichaels, S. A., et al. | February 19, 2021In this manuscript we discuss emerging drug development tools that can be used to accelerate…emcguinnFebruary 19, 2021 Read More
Publications of the Week T Cells Specific for a Mycobacterial Glycolipid Expand after Intravenous Bacillus Calmette–Guérin VaccinationLayton, E. D., et al. | February 18, 2021Peptide antigens are typically presented to T cells by highly polymorphic major histocompatibility complex (MHC)…emcguinnFebruary 18, 2021 Read More