Publications of the Week New Immuno-Oncology Targets and Resistance Mechanisms Takez, M. C., et al. | August 25, 2022 Immune checkpoint inhibition (ICI) has revolutionized the field of non-small cell lung cancer (NSCLC); currently,…pthomsonAugust 25, 2022 Read More
Publications of the Week Tissue Oxygenation Stabilizes Neovessels and Mitigates Hemorrhages in Human Atherosclerosis-Induced Angiogenesis A. C. Aplin & R. F. Nicosia | August 17, 2022 The authors used novel ex vivo and in vivo models to characterize the effect of…dcorriganAugust 17, 2022 Read More
Publications of the Week Bladder Cancer Patient-Derived Organoids and Avatars for Personalized Cancer Discovery Soo Kim, Y., Hsieh, A. C., and Lam, H. M. | August 16, 2022 Prediction of treatment response has attracted growing attention in cancer research to improve clinical outcomes…dcorriganAugust 16, 2022 Read More
Publications of the Week Discovery of a Transferrin Receptor 1-Binding Aptamer and Its Application in Cancer Cell Depletion for Adoptive T Cell Therapy Manufacturing Cheng, E. L., et al. | August 12, 2022 The authors report a new high-affinity aptamer that binds to the transferrin receptor, also called…dcorriganAugust 12, 2022 Read More
Publications of the Week Breath of Fresh Air: Towards Unraveling the Molecular Underpinnings of Sleep Apnea | August 12, 2022 Obstructive sleep apnea (OSA) is an important risk factor for multiple diseases (1). 425 million…dcorriganAugust 12, 2022 Read More
Publications of the Week Sustained Inhibition of NPY/AgRP Neuronal Activity by FGF1 Hwang, E., et al. | August 5, 2022 In rodent models of type 2 diabetes (T2D), central administration of fibroblast growth factor 1…dcorriganAugust 5, 2022 Read More
Publications of the Week An In Vivo Model of Human Macrophages in Metastatic Melanoma Voillet, V., et al. | August 4, 2022 Despite recent therapeutic progress, advanced melanoma remains lethal for many patients. The composition of the…dcorriganAugust 4, 2022 Read More
Publications of the Week Intraosseous Delivery of Platelet-Targeted FVIII Lentiviral Vector in Humanized NBSGW Mice Hoyoung Joo, J., et al. | July 29, 2022 Read the Publication This week we profile a recent publication in Blood Advances from the…dcorriganJuly 29, 2022 Read More
Publications of the Week Pharmacological Targeting of TFIIH Suppresses KRAS Mutant Pancreatic Ductal Adenocarcinoma and Synergizes with TRAIL Moser, R., et al. | July 29, 2022 Pancreatic ductal adenocarcinoma (PDAC) typically presents as metastatic disease at diagnosis and remains refractory to…dcorriganJuly 29, 2022 Read More
Publications of the Week Mucosal Viral Infection Induces a Regulatory T Cell Activation Phenotype Distinct from Tissue Residency in Mouse and Human Tissues Traxinger, B. R., et al. | July 21, 2022 The authors' work contributes to a growing research body on mucosal tissue regulatory T cells…dcorriganJuly 21, 2022 Read More