Publications of the Week Sustained Inhibition of NPY/AgRP Neuronal Activity by FGF1 Hwang, E., et al. | August 5, 2022 In rodent models of type 2 diabetes (T2D), central administration of fibroblast growth factor 1…dcorriganAugust 5, 2022 Read More
Publications of the Week An In Vivo Model of Human Macrophages in Metastatic Melanoma Voillet, V., et al. | August 4, 2022 Despite recent therapeutic progress, advanced melanoma remains lethal for many patients. The composition of the…dcorriganAugust 4, 2022 Read More
Publications of the Week Intraosseous Delivery of Platelet-Targeted FVIII Lentiviral Vector in Humanized NBSGW Mice Hoyoung Joo, J., et al. | July 29, 2022 Read the Publication This week we profile a recent publication in Blood Advances from the…dcorriganJuly 29, 2022 Read More
Publications of the Week Pharmacological Targeting of TFIIH Suppresses KRAS Mutant Pancreatic Ductal Adenocarcinoma and Synergizes with TRAIL Moser, R., et al. | July 29, 2022 Pancreatic ductal adenocarcinoma (PDAC) typically presents as metastatic disease at diagnosis and remains refractory to…dcorriganJuly 29, 2022 Read More
Publications of the Week Mucosal Viral Infection Induces a Regulatory T Cell Activation Phenotype Distinct from Tissue Residency in Mouse and Human Tissues Traxinger, B. R., et al. | July 21, 2022 The authors' work contributes to a growing research body on mucosal tissue regulatory T cells…dcorriganJuly 21, 2022 Read More
Publications of the Week TOLLIP Optimizes Dendritic Cell Maturation to Lipopolysaccharide and Mycobacterium tuberculosis Venkatasubramanian, S., et al. | July 19, 2022 The authors found that TOLLIP, a gene associated with TB susceptibility, influences dendritic cell maturation,…dcorriganJuly 19, 2022 Read More
Publications of the Week A Slow Dynamic RNA Switch Regulates Processing of microRNA-21 Shortridge, M. D., et al. | July 15, 2022 The microRNAs are non-coding RNAs which post-transcriptionally regulate the expression of many eukaryotic genes, and whose dysregulation…dcorriganJuly 15, 2022 Read More
Publications of the Week Analysis of the HVTN 702 Phase 2b-3 HIV-1 Vaccine Trial in South Africa Assessing RV144 Antibody and T Cell Correlates of HIV-1 Acquisition Risk Moodie, Z., et al. | July 14, 2022 Read the Publication This week we profile a recent publication in The Journal of Infectious…dcorriganJuly 14, 2022 Read More
Publications of the Week Development of a Primary Human Intestinal Epithelium Enriched in L-Cells for Assay of GLP-1 Secretion Villegas-Novoa, C., et al. | July 8, 2022 Type 2 diabetes mellitus is a chronic disease associated with obesity and dysregulated human feeding…dcorriganJuly 8, 2022 Read More
Publications of the Week Mapping Functional Regions of Essential Bacterial Proteins with Dominant-Negative Protein Fragments Savinov, A., Fernandez, A., and Fields, S. | July 7, 2022 Peptide fragments can inhibit the interactions of the full-length proteins from which the fragments derive. The…dcorriganJuly 7, 2022 Read More