Publications of the Week

Although somatic mutations in colorectal cancer are well characterized, little is known about the accumulation…

The authors showed that TGF-β signaling in smooth muscle cells during embryogenesis and early postnatal…

Read the Publication This week we profile a recent publication in Leukemia from Dr. George…

The authors show that a commonly occurring type of somatic mutation, loss of heterozygosity (LOH),…

Differential interleukin-2 (IL-2) signaling and production are associated with disparate effector and memory fates. Whether…

Developmental abnormalities of the cerebellum are among the most recognized structural brain malformations in human…

The authors show that only a subset of the CD4+ T cells that are present…

Mutations in BRCA1 and BARD1 predispose carriers to breast and ovarian cancers. The BRCA1 and BARD1 proteins form a…

Studies of de novo mutation (DNM) have typically excluded some of the most repetitive and complex regions…

One key barrier to curative therapies for HIV is the limited understanding of HIV persistence.…