The Fbw7 ubiquitin ligase targets many proteins for proteasomal degradation, which include oncogenic transcription factors…
dcorriganMarch 9, 2022
Cryo-ET of Env on Intact HIV Virions Reveals Structural Variation and Positioning on the Gag Lattice
HIV-1 Env mediates viral entry into host cells and is the sole target for neutralizing…
Dynamic fibroblast to myofibroblast state transitions underlie the heart’s fibrotic response. Because transcriptome maturation by…
dcorriganMarch 2, 2022
Small molecule adjuvants that enhance the activity of established antibiotics represent promising agents in the…
dcorriganFebruary 25, 2022
“Molecular glue” (MG) is a term coined to describe the mechanism of action of the…
dcorriganFebruary 22, 2022
While antivirals are often effective at preventing and treating HSV and VZV following transplant, there…
dcorriganFebruary 21, 2022
The authors discovered unexpected novelty and innovation during the evolution of essential DNA-packing proteins, called…
dcorriganFebruary 18, 2022
The authors found an additional family of RNA binding proteins/processing factors in the alyref homologs…
dcorriganFebruary 16, 2022
Understanding cortical microcircuits requires thorough measurement of physiological properties of synaptic connections formed within and…
dcorriganFebruary 14, 2022
The authors suggest that brain endothelial cells can have different responses to injury depending on…
dcorriganFebruary 11, 2022
