Publications of the Week Whole-Blood Cytokine Secretion Assay as a High-Throughput Alternative for Assessing the Cell-Mediated Immunity Profile after Two Doses of an Adjuvanted SARS-CoV-2 Recombinant Protein Vaccine Candidate De Rosa, S. C., et al. | January 18, 2022 We previously described the Phase I-II evaluation of SARS-CoV-2 recombinant protein candidate vaccine, CoV2-PreS-dTM, with…dcorriganJanuary 18, 2022 Read More
Publications of the Week Deep Immune Phenotyping Reveals Similarities between Aging, Down Syndrome, and Autoimmunity Lambert, K., et al. | January 13, 2022 Individuals with Down syndrome show cellular and clinical features of dysregulated aging of the immune…dcorriganJanuary 13, 2022 Read More
Publications of the Week Antibody-Mediated Broad Sarbecovirus Neutralization through ACE2 Molecular Mimicry Park, Y., et al. | January 10, 2022 Understanding broadly neutralizing sarbecovirus antibody responses is key to developing countermeasures against SARS-CoV-2 variants and…dcorriganJanuary 10, 2022 Read More
Publications of the Week Redirecting Meiotic DNA Break Hotspot Determinant Proteins Alters Localized Spatial Control of DNA Break Formation and Repair Hyppa, R. W., et al. | January 7, 2022 During meiosis, DNA double-strand breaks (DSBs) are formed at high frequency at special chromosomal sites,…dcorriganJanuary 7, 2022 Read More
Publications of the Week Cross-Reactive and Mono-Reactive SARS-CoV-2 CD4+ T Cells in Prepandemic and COVID-19 Convalescent Individuals Johansson, A. M., et al. | January 6, 2022 Class II tetramer reagents for eleven common DR alleles and a DP allele prevalent in…dcorriganJanuary 6, 2022 Read More
Publications of the Week TAOK2 Is an ER-Localized Kinase That Catalyzes the Dynamic Tethering of ER to Microtubules Nourbakhsh, K., et al. | December 16, 2021 The endoplasmic reticulum (ER) depends on extensive association with the microtubule (MT) cytoskeleton for its…sciencecityDecember 16, 2021 Read More
Publications of the Week Coordinated Mis-Splicing of TMEM14C and ABCB7 Causes Ring Sideroblast Formation in SF3B1-Mutant Myelodysplastic Syndrome Clough, C., et al. | December 14, 2021 SF3B1 splicing factor mutations are near-universally found in myelodysplastic syndromes (MDS) with ring sideroblasts, a clonal…dcorriganDecember 14, 2021 Read More
Publications of the Week Information Flow in the Spatiotemporal Organization of Immune Responses Huang, J., Lyons-Cohen, M., and Gerner, M. | December 10, 2021 Immune responses must be rapid, tightly orchestrated, and tailored to the encountered stimulus. Lymphatic vessels…dcorriganDecember 10, 2021 Read More
Publications of the Week Discrete Regulatory Modules Instruct Hematopoietic Lineage Commitment and Differentiation Georgolopoulos, G., et al. | December 9, 2021 Lineage commitment and differentiation is driven by the concerted action of master transcriptional regulators at…dcorriganDecember 9, 2021 Read More
Publications of the Week Drug Delivery to the Central Nervous System Nance, E., et al. | December 8, 2021 Despite the rising global incidence of central nervous system (CNS) disorders, CNS drug development remains…dcorriganDecember 8, 2021 Read More