Publications of the Week In Vivo Antiviral Host Transcriptional Response to SARS-CoV-2 by Viral Load, Sex, and AgeLieberman, N., et al. | September 18, 2020Despite limited genomic diversity, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has shown a wide…emcguinnSeptember 18, 2020 Read More
Publications of the Week MHC Class II Transactivator CIITA Induces Cell Resistance to Ebola Virus and SARS-Like CoronavirusesBruchez, A., et al. | September 17, 2020The authors have found a new pathway of cell resistance to viruses that is broad,…eabramovichSeptember 17, 2020 Read More
Publications of the Week Designed Protein Logic to Target Cells with Precise Combinations of Surface AntigensLajoie, M., et al. | September 15, 2020Precise cell targeting is challenging because most mammalian cell types lack a single surface marker…emcguinnSeptember 15, 2020 Read More
Publications of the Week Hypothalamic Perineuronal Net Assembly Is Required for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1 in RatsAlonge, K., et al. | September 11, 2020We recently showed that perineuronal nets (PNNs) enmesh glucoregulatory neurons in the arcuate nucleus (Arc)…emcguinnSeptember 11, 2020 Read More
Publications of the Week Infarct Collagen Topography Regulates Fibroblast Fate via p38-Yap-TEAD SignalsBugg, D., et al. | September 9, 2020Rationale: Myocardial infarction (MI) causes spatial variation in collagen organization and phenotypic diversity in fibroblasts, which…emcguinnSeptember 9, 2020 Read More
Publications of the Week Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19Rodda, L., et al. | September 4, 2020The recently emerged SARS-CoV-2 virus is currently causing a global pandemic and cases continue to…emcguinnSeptember 4, 2020 Read More
Publications of the Week Metabolic Excretion Associated with Nutrient–Growth Dysregulation Promotes the Rapid Evolution of an Overt Metabolic DefectGreen. R., et al. | September 3, 2020In eukaryotes, conserved mechanisms ensure that cell growth is coordinated with nutrient availability. Overactive growth…emcguinnSeptember 3, 2020 Read More
Publications of the Week CBFB-MYH11 Fusion Neoantigen Enables T Cell Recognition and Killing of Acute Myeloid LeukemiaBiernacki, M., et al. | August 27, 2020Proteins created from recurrent fusion genes like CBFB-MYH11 are prevalent in acute myeloid leukemia (AML), often necessary…emcguinnAugust 27, 2020 Read More
Publications of the Week Gene Editing and Elimination of Latent Herpes Simplex Virus In VivoAubert, M., et al. | August 25, 2020We evaluate gene editing of HSV in a well-established mouse model, using adeno-associated virus (AAV)-delivered…emcguinnAugust 25, 2020 Read More
Publications of the Week Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19Rodda, L., et al. | August 24, 2020The recently emerged SARS-CoV-2 virus is currently causing a global pandemic and cases continue to…emcguinnAugust 24, 2020 Read More