Publications of the Week Identification of In Vivo Hox13-Binding Sites Reveals an Essential Locus Controlling Zebrafish Brachyury Expression Ye, Z., et al. | June 8, 2021 My lab studies how the early vertebrate embryo forms using zebrafish as a model system.…kchenJune 8, 2021 Read More
Publications of the Week Live-Attenuated RNA Hybrid Vaccine Technology Provides Single-Dose Protection against Chikungunya Virus Voigt, A. E., at al. | June 7, 2021 We present a live-attenuated RNA hybrid vaccine technology which uses an RNA vaccine delivery vehicle…kchenJune 7, 2021 Read More
Publications of the Week A Taxonomy of Transcriptomic Cell Types across the Isocortex and Hippocampal Formation Yao, Z., et al. | June 2, 2021 Our team at the Allen Institute for Brain Science studies cell type diversity in the…kchenJune 2, 2021 Read More
Publications of the Week mRNA Translation Is a Therapeutic Vulnerability Necessary for Bladder Epithelial Transformation Jana, S., et al. | June 1, 2021 Our laboratory studies the process of mRNA translation in normal cell physiology and disease. We…kchenJune 1, 2021 Read More
Publications of the Week Selective Androgen Receptor Modulators Activate the Canonical Prostate Cancer Androgen Receptor Program and Repress Cancer Growth Nyquist, D. M., et al. | May 28, 2021 Prostate cancer (PC) is driven by androgen receptor (AR) activity, a master regulator of prostate…kchenMay 28, 2021 Read More
Publications of the Week A Photoswitchable GPCR-Based Opsin for Presynaptic Inhibition Copits, A. B., et al. | May 26, 2021 The authors focus on neuromodulatory processing in the brain, as it relates to effective behavior.…kchenMay 26, 2021 Read More
Publications of the Week Enhancer Viruses for Combinatorial Cell-Subclass-Specific Labeling Daigle, L. T., et al. | May 20, 2021 The authors are developing adeno-associated viruses (AAVs) and transgenic tools to target and perturb a…kchenMay 20, 2021 Read More
Publications of the Week Tissue Context Determines the Penetrance of Regulatory DNA Variation Halow, M. J., et al. | May 19, 2021 Functional assessment of disease-associated sequence variation at non-coding regulatory elements is complicated by their high…kchenMay 19, 2021 Read More
Publications of the Week Structural Basis for Broad Coronavirus Neutralization Sauer, M. M., et al. | May 14, 2021 Three highly pathogenic β-coronaviruses have crossed the animal-to-human species barrier in the past two decades:…kchenMay 14, 2021 Read More
Publications of the Week Tumor-Associated Autoantibodies from Mouse Breast Cancer Models Are Found in Serum of Breast Cancer Patients Stanton, E., S. et al. | May 14, 2021 B cell responses to tumor antigens occur early in breast tumors and may identify immunogenic…kchenMay 14, 2021 Read More