Publications of the Week Autophosphorylation Is Sufficient to Release Mps1 Kinase from Native KinetochoresKoch, L.B., et al. | August 22, 2019If even a single chromosome is unattached or incorrectly attached, an enzyme, Mps1, initiates checkpoint…sciencecityAugust 22, 2019 Read More
Publications of the Week Detection and Activation of HIV Broadly Neutralizing Antibody Precursor B Cells Using Anti-IdiotypesBancroft, T., et al. | August 19, 2019The authors merged an old technology, anti-idiotypes, showing that it could be paired with newer…sciencecityAugust 19, 2019 Read More
Publications of the Week Epicardial Cells Derived from Human Embryonic Stem Cells Augment Cardiomyocyte-Driven Heart RegenerationBargehr, J., et al. | August 16, 2019The authors previously showed that transplanting human heart muscle cells into myocardial infarcts resulted in…sciencecityAugust 16, 2019 Read More
Publications of the Week Therapeutically Relevant Engraftment of a CRISPR-Cas9–Edited HSC-Enriched Population with HbF Reactivation in Nonhuman PrimatesHumbert, O., et al. | August 14, 2019The CRISPR/Cas9 technology offers many opportunities to treat genetic and infectious diseases, but safety of…sciencecityAugust 14, 2019 Read More
Publications of the Week The Androgen Receptor Regulates a Druggable Translational Regulon in Advanced Prostate CancerLiu, Y., et al. | August 12, 2019Most prostate cancers are initially addicted to androgens and the androgen receptor, which they use…sciencecityAugust 12, 2019 Read More
Publications of the Week Rethinking the Role of the Brain in Glucose Homeostasis and Diabetes PathogenesisBrown, J.M., et al. | August 9, 2019The brain plays a major role in homeostatic processes ranging from control of body temperature…sciencecityAugust 9, 2019 Read More
Publications of the Week Epitope Targeting with Self-Assembled Peptide VaccinesZeigler, D.F., et al. | August 7, 2019Nanoparticle-based delivery systems are being used to simplify and accelerate new vaccine development. Previously, we…sciencecityAugust 7, 2019 Read More
Publications of the Week High Prevalence and Disease Correlation of Autoantibodies against p40 Encoded by Long Interspersed Nuclear Elements (LINE-1) in Systemic Lupus ErythematosusCarter, V., et al. | August 5, 2019This paper describes evidence that a retroelement in our genome, called LINE-1, is active in…sciencecityAugust 5, 2019 Read More
Publications of the Week A Pro-Inflammatory CD8+ T-Cell Subset Patrols the Cervicovaginal TractPattacini, L., et al. | August 1, 2019The immune system of the cervicovaginal tract (CVT) must balance immunosurveillance and active immunity against…sciencecityAugust 1, 2019 Read More
Publications of the Week DUX4 Suppresses MHC Class I to Promote Cancer Immune Evasion and Resistance to Checkpoint BlockadeChew, G., et al. | July 30, 2019Advances in cancer immunotherapies make it critical to identify genes that modulate antigen presentation and…sciencecityJuly 30, 2019 Read More