Publications of the Week A Petascale Automated Imaging Pipeline for Mapping Neuronal Circuits with High-Throughput Transmission Electron MicroscopyDa Costa, N., et al. | October 15, 2020Electron microscopy (EM) is widely used for studying cellular structure and network connectivity in the brain.…emcguinnOctober 15, 2020 Read More
Publications of the Week De Novo Induction of Lineage Plasticity from Human Prostate Luminal Epithelial Cells by Activated AKT1 and C-MycKwon, O., et al. | October 8, 2020Neuroendocrine prostate cancer (NEPC) is an aggressive variant of prostate cancer that either develops de…emcguinnOctober 8, 2020 Read More
Publications of the Week Ultrapotent Human Antibodies Protect Against SARS-CoV-2 Challenge via Multiple MechanismsTortorici, M., et al. | October 5, 2020Efficient therapeutic options are needed to control the spread of SARS-CoV-2 that has caused more…emcguinnOctober 5, 2020 Read More
Publications of the Week Raman-Guided Subcellular Pharmaco-Metabolomics for Metastatic Melanoma CellsDu, J., et al. | October 2, 2020Non-invasively probing metabolites within single live cells is highly desired but challenging. Here we utilize…emcguinnOctober 2, 2020 Read More
Publications of the Week Ontogeny of Different Subsets of Yellow Fever Virus-Specific Circulatory CXCR5+ CD4+ T Cells after Yellow Fever VaccinationDeGottardi, Q., et al. | September 30, 2020Monitoring the frequency of circulatory CXCR5+ (cCXCR5+) CD4+ T cells in periphery blood provides a potential biomarker…emcguinnSeptember 30, 2020 Read More
Publications of the Week The Optoretinogram Reveals the Primary Steps of Phototransduction in the Living Human EyePandiyan, V., et al. | September 23, 2020Photoreceptors initiate vision by converting photons to electrical activity. The onset of the phototransduction cascade…emcguinnSeptember 23, 2020 Read More
Publications of the Week Histone Deposition Pathways Determine the Chromatin Landscapes of H3.1 and H3.3 K27M OncohistonesHenikoff, S., et al. | September 21, 2020Lysine 27-to-methionine (K27M) mutations in the H3.1 or H3.3 histone genes are characteristic of pediatric…emcguinnSeptember 21, 2020 Read More
Publications of the Week In Vivo Antiviral Host Transcriptional Response to SARS-CoV-2 by Viral Load, Sex, and AgeLieberman, N., et al. | September 18, 2020Despite limited genomic diversity, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has shown a wide…emcguinnSeptember 18, 2020 Read More
Publications of the Week MHC Class II Transactivator CIITA Induces Cell Resistance to Ebola Virus and SARS-Like CoronavirusesBruchez, A., et al. | September 17, 2020The authors have found a new pathway of cell resistance to viruses that is broad,…eabramovichSeptember 17, 2020 Read More
Publications of the Week Designed Protein Logic to Target Cells with Precise Combinations of Surface AntigensLajoie, M., et al. | September 15, 2020Precise cell targeting is challenging because most mammalian cell types lack a single surface marker…emcguinnSeptember 15, 2020 Read More