Publications of the Week Endomembrane Targeting of Human OAS1 p46 Augments Antiviral Activity Soveg, F., et al. | August 23, 2021 Lead authors Frank Soveg and Johannes Schwerk identified a membrane-targeted gene, OAS1 p46, with strong…dcorriganAugust 23, 2021 Read More
Publications of the Week The Redox-Responsive Transcriptional Regulator Rex Represses Fermentative Metabolism and Is Required for Listeria monocytogenes Pathogenesis Halsey, C., et al. | August 20, 2021 In this work, we characterized the role of the redox-responsive transcriptional regulator Rex in Listeria…dcorriganAugust 20, 2021 Read More
Publications of the Week Massively Parallel Characterization of CYP2C9 Variant Enzyme Activity and Abundance Amorosi, C., et al. | August 20, 2021 Scientists only have accurate dosage advice for a small number of the most well-studied genetic…dcorriganAugust 20, 2021 Read More
Publications of the Week A Subpopulation of Microglia Generated in the Adult Mouse Brain Originate from Prominin-1 Expressing Progenitors Prater, K., et. al | August 19, 2021 Microglia maintain brain health and play important roles in disease and injury. Despite their known…dcorriganAugust 19, 2021 Read More
Publications of the Week Antibody Interference by a Non-Neutralizing Antibody Abrogates Humoral Protection against Plasmodium yoelii Liver Stage Vijayan, K., et al. | August 13, 2021 Most work on the development of malaria vaccines happens in laboratory or clinical trials, where…dcorriganAugust 13, 2021 Read More
Publications of the Week Integrative Oncogene-Dependency Mapping Identifies RIT1 Vulnerabilities and Synergies in Lung Cancer Vichas, A. et al. | August 12, 2021 CRISPR-based cancer dependency maps are accelerating advances in cancer precision medicine, but adequate functional maps…dcorriganAugust 12, 2021 Read More
Publications of the Week A Rationally Designed C-Di-AMP FRET Biosensor to Monitor Nucleotide Dynamics Pollock, A. J., et al. | August 10, 2021 3’3’-cyclic di-adenosine monophosphate (c-di-AMP) is an important nucleotide second messenger found throughout the bacterial domain…dcorriganAugust 10, 2021 Read More
Publications of the Week Characterization of Neoantigen-Specific T Cells in Cancer Resistant to Immune Checkpoint Therapies Li, S., et al. | August 6, 2021 The lab focuses on analyzing cellular immune responses in the context of cancer and infectious…dcorriganAugust 6, 2021 Read More
Publications of the Week RNA Splicing Factors SRRM3 and SRRM4 Distinguish Molecular Phenotypes of Castration-Resistant Neuroendocrine Prostate Cancer Labrecque, M., et al. | August 2, 2021 Neuroendocrine (NE) differentiation in metastatic castration-resistant prostate cancer (mCRPC) is an increasingly common clinical feature…kchenAugust 2, 2021 Read More
Publications of the Week Allergic Aspects of IgG4-Related Disease: Implications for Pathogenesis and Therapy Michailidou, D., et. al | July 29, 2021 IgG4-related disease (IgG4-RD) is a rare systemic fibroinflammatory disease frequently associated with allergy. The pathogenesis…dcorriganJuly 29, 2021 Read More