Intracellular pathogens alter their host cells' mechanics to promote dissemination through tissues. Conversely, host cells…
kchenMarch 8, 2021
Long-read and strand-specific sequencing technologies together facilitate the de novo assembly of high-quality haplotype-resolved human…
kchenMarch 4, 2021
The work discussed here highlights our work on gap junctions. Gap junctions are highly organized…
kchenMarch 4, 2021
The research in our lab focuses on the smallest blood vessels that deliver oxygen and…
kchenFebruary 26, 2021
Using a gain-of-function screen in Drosophila, we identified the Krüppel-like factor Cabut (Cbt) as a…
kchenFebruary 24, 2021
There is increasing interest in targeting CD33 in malignant and non-malignant disorders. In acute myeloid…
kchenFebruary 22, 2021
Mutations in the E3 ubiquitin ligase RING domains of BRCA1/BARD1 predispose carriers to breast and…
kchenFebruary 19, 2021
In this manuscript we discuss emerging drug development tools that can be used to accelerate…
emcguinnFebruary 19, 2021
Peptide antigens are typically presented to T cells by highly polymorphic major histocompatibility complex (MHC)…
emcguinnFebruary 18, 2021
