Publications of the Week Resolving the Synaptic versus Developmental Dichotomy of Autism Risk GenesHeavner, W.H., & Smith, S.E.P. | April 10, 2020Autism Spectrum Disorder (ASD) risk genes are often described as either developmental or synaptic. However,…sciencecityApril 10, 2020 Read More
Publications of the Week Phenomics-Based Quantification of CRISPR-Induced Mosaicism in ZebrafishWatson, C.J., et al. | April 8, 2020This manuscript provides validation of an approach to rapidly screen zebrafish using first-generation CRISPR-edited mutants…sciencecityApril 8, 2020 Read More
Publications of the Week Dimensionality Reduction by UMAP to Visualize Physical and Genetic InteractionsDorrity, M.W., et al. | April 3, 2020Dimensionality reduction is often used to visualize complex expression profiling data. Here, we use the…sciencecityApril 3, 2020 Read More
Publications of the Week RecV Recombinase System for In Vivo Targeted Optogenomic Modifications of Single Cells or Cell PopulationsYao, S., et al. | April 1, 2020Brain circuits comprise vast numbers of interconnected neurons with diverse molecular, anatomical and physiological properties.…sciencecityApril 1, 2020 Read More
Publications of the Week Remnants of the Triglyceride-Rich Lipoproteins, Diabetes, and Cardiovascular DiseaseChait, A., et al. | March 26, 2020Diabetes is now a pandemic disease. Moreover, a large number of people with prediabetes are…sciencecityMarch 26, 2020 Read More
Publications of the Week Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-Helminth Immunity in the Small Intestine But Are Dispensable for Anti-Protist ImmunityMcGinty, J.W., et al. | March 23, 2020How do tuft cells regulate type 2 immune responses? Initial work identified the cytokine IL-25…sciencecityMarch 23, 2020 Read More
Publications of the Week Tissue-Resident T Cell Derived Cytokines Eliminate Herpes Simplex Virus-2 Infected CellsRoychoudhury, P., et al. | March 19, 2020The authors have developed a realistic 3D model which captures the mechanisms that allow a…sciencecityMarch 19, 2020 Read More
Publications of the Week The Functional Activity of E-Cadherin Controls Tumor Cell Metastasis at Multiple StepsNa, TY., et al. | March 18, 2020The expression of E-cadherin has been implicated in tumor metastasis, often as a tumor suppressor,…sciencecityMarch 18, 2020 Read More
Publications of the Week Engineering Heart MorphogenesisMandrycky, C.J., et al. | March 16, 2020There is high potential for current technologies to be used to recapitulate heart developmentĀ in vitro…sciencecityMarch 16, 2020 Read More
Publications of the Week Candidate Silencer Elements for the Human and Mouse GenomesJayavelu, N.D., et al. | March 12, 2020The study of gene regulation is dominated by a focus on the control of gene…sciencecityMarch 12, 2020 Read More