Publications of the Week The Optoretinogram Reveals the Primary Steps of Phototransduction in the Living Human Eye Pandiyan, V., et al. | September 23, 2020 Photoreceptors initiate vision by converting photons to electrical activity. The onset of the phototransduction cascade…emcguinnSeptember 23, 2020 Read More
Publications of the Week Histone Deposition Pathways Determine the Chromatin Landscapes of H3.1 and H3.3 K27M Oncohistones Henikoff, S., et al. | September 21, 2020 Lysine 27-to-methionine (K27M) mutations in the H3.1 or H3.3 histone genes are characteristic of pediatric…emcguinnSeptember 21, 2020 Read More
Publications of the Week In Vivo Antiviral Host Transcriptional Response to SARS-CoV-2 by Viral Load, Sex, and Age Lieberman, N., et al. | September 18, 2020 Despite limited genomic diversity, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has shown a wide…emcguinnSeptember 18, 2020 Read More
Publications of the Week MHC Class II Transactivator CIITA Induces Cell Resistance to Ebola Virus and SARS-Like Coronaviruses Bruchez, A., et al. | September 17, 2020 The authors have found a new pathway of cell resistance to viruses that is broad,…eabramovichSeptember 17, 2020 Read More
Publications of the Week Designed Protein Logic to Target Cells with Precise Combinations of Surface Antigens Lajoie, M., et al. | September 15, 2020 Precise cell targeting is challenging because most mammalian cell types lack a single surface marker…emcguinnSeptember 15, 2020 Read More
Publications of the Week Hypothalamic Perineuronal Net Assembly Is Required for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1 in Rats Alonge, K., et al. | September 11, 2020 We recently showed that perineuronal nets (PNNs) enmesh glucoregulatory neurons in the arcuate nucleus (Arc)…emcguinnSeptember 11, 2020 Read More
Publications of the Week Infarct Collagen Topography Regulates Fibroblast Fate via p38-Yap-TEAD Signals Bugg, D., et al. | September 9, 2020 Rationale: Myocardial infarction (MI) causes spatial variation in collagen organization and phenotypic diversity in fibroblasts, which…emcguinnSeptember 9, 2020 Read More
Publications of the Week Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19 Rodda, L., et al. | September 4, 2020 The recently emerged SARS-CoV-2 virus is currently causing a global pandemic and cases continue to…emcguinnSeptember 4, 2020 Read More
Publications of the Week Metabolic Excretion Associated with Nutrient–Growth Dysregulation Promotes the Rapid Evolution of an Overt Metabolic Defect Green. R., et al. | September 3, 2020 In eukaryotes, conserved mechanisms ensure that cell growth is coordinated with nutrient availability. Overactive growth…emcguinnSeptember 3, 2020 Read More
Publications of the Week CBFB-MYH11 Fusion Neoantigen Enables T Cell Recognition and Killing of Acute Myeloid Leukemia Biernacki, M., et al. | August 27, 2020 Proteins created from recurrent fusion genes like CBFB-MYH11 are prevalent in acute myeloid leukemia (AML), often necessary…emcguinnAugust 27, 2020 Read More