Publications of the Week Engineering Heart MorphogenesisMandrycky, C.J., et al. | March 16, 2020There is high potential for current technologies to be used to recapitulate heart development in vitro…sciencecityMarch 16, 2020 Read More
Publications of the Week Candidate Silencer Elements for the Human and Mouse GenomesJayavelu, N.D., et al. | March 12, 2020The study of gene regulation is dominated by a focus on the control of gene…sciencecityMarch 12, 2020 Read More
Publications of the Week Spatial Modeling of Prostate Cancer Metabolic Gene Expression Reveals Extensive Heterogeneity and Selective VulnerabilitiesWang, Y., et al. | March 10, 2020Targeting metabolic aberrations has been a major focus in cancer research, and genome-scale metabolic network…sciencecityMarch 10, 2020 Read More
Publications of the Week The CD33 Splice Isoform Lacking Exon 2 as Therapeutic Target in Human Acute Myeloid LeukemiaGodwin, C.D., et al. | March 6, 2020Data from several randomized studies have shown that a CD33 antibody-drug conjugate reduces relapse risks…sciencecityMarch 6, 2020 Read More
Publications of the Week Increased Islet Antigen–Specific Regulatory and Effector CD4+ T Cells in Healthy Individuals with the Type 1 Diabetes–Protective HaplotypeWen, X., et al. | March 3, 2020Polymorphic histocompatibility genes in the HLA locus have a strong influence on genetic susceptibility to…sciencecityMarch 3, 2020 Read More
Publications of the Week STAT Signaling Modifies Ascl1 Chromatin Binding and Limits Neural Regeneration from Muller Glia in Adult Mouse RetinaJorstad, N.L., et al. | February 27, 2020Müller glia (MG) serve as sources for retinal regeneration in non-mammalian vertebrates. We find that…sciencecityFebruary 27, 2020 Read More
Publications of the Week Embryonic Barcoding of Equipotent Mammary Progenitors Functionally Identifies Breast Cancer DriversYing, Z., & Beronja, S., | February 24, 2020Identification of clinically relevant drivers of breast cancers in intact mammary epithelium is critical for…sciencecityFebruary 24, 2020 Read More
Publications of the Week Connect-Seq to Superimpose Molecular on Anatomical Neural Circuit MapsHanchate, N.K., et al. | February 21, 2020Single-cell transcriptomics has emerged as a powerful means to define the molecular heterogeneity of brain…sciencecityFebruary 21, 2020 Read More
Publications of the Week Mechanisms of Endogenous HIV-1 Reactivation by Endocervical Epithelial CellsGornalusse, G.G., et al. | February 20, 2020The authors have demonstrated that the immunological activities of certain epithelial cells, in this case…sciencecityFebruary 20, 2020 Read More
Publications of the Week Broadly Neutralizing Antibodies for HIV PreventionKaruna, S.T., & Corey, L. | February 13, 2020In the last decade, over a dozen potent broadly neutralizing antibodies (bnAbs) to several HIV…sciencecityFebruary 13, 2020 Read More