Publications of the Week Assembly of the Threespine Stickleback Y Chromosome Reveals Convergent Signatures of Sex Chromosome Evolution Peichel, C., et al. | July 24, 2020 Heteromorphic sex chromosomes have evolved repeatedly across diverse species. Suppression of recombination between X and…emcguinnJuly 24, 2020 Read More
Publications of the Week Robust Expansion of HIV CAR T Cells following Antigen Boosting in ART-Suppressed Nonhuman Primates Rust, B., et al. | July 22, 2020 The authors observed that virus-specific CAR T-cells were less functional in vivo, relative to CAR T-cells…emcguinnJuly 22, 2020 Read More
Publications of the Week Small-Molecule Sensitization of RecBCD Helicase–Nuclease to a Chi Hotspot-Activated State Karabulut, A., et al. | July 17, 2020 We study a small molecule (NSAC1003) that one of our collaborators (Ryan Cirz) at Achaogen,…emcguinnJuly 17, 2020 Read More
Publications of the Week Dissemination of RasV12-Transformed Cells Requires the Mechanosensitive Channel Piezo Lee, J., et al. | July 17, 2020 Dissemination of transformed cells is a key process in metastasis. Despite its importance, how transformed…emcguinnJuly 17, 2020 Read More
Publications of the Week KSHV Requires vCyclin to Overcome Replicative Senescence in Primary Human Lymphatic Endothelial Cells DiMaio, T., et al. | July 10, 2020 Kaposi’s Sarcoma Herpesvirus (KSHV) is present in the main tumor cells of Kaposi’s Sarcoma (KS),…emcguinnJuly 10, 2020 Read More
Publications of the Week Cytosolic Delivery of Proteins by Cholesterol Tagging Tai, W., et al. | July 7, 2020 Protein-based imaging agents and therapeutics are superior in structural and functional diversity compared to small…eabramovichJuly 7, 2020 Read More
Publications of the Week Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity Han, CY et al. | July 3, 2020 Obesity is characterized by adipose tissue inflammation. Because proteoglycans regulate inflammation, here we investigate their…eabramovichJuly 3, 2020 Read More
Publications of the Week Mitochondrial Protein Interaction Landscape of SS-31 Chavez, J., et al. | June 29, 2020 SS-31 is a synthetic peptide that improves mitochondrial function and is currently undergoing clinical trials…emcguinnJune 29, 2020 Read More
Publications of the Week Human Tumor-Infiltrating MAIT Cells Display Hallmarks of Bacterial Antigen Recognition in Colorectal Cancer Li, S., et al. | June 26, 2020 Growing evidence indicates a role for the gut microbiota in modulating anti-tumor treatment efficacy in…emcguinnJune 26, 2020 Read More
Publications of the Week Weaker Neural Suppression in Autism Schallmo, M., et al. | June 18, 2020 Our paper investigates differences in visual perception in people with autism versus neurotypical individuals. People…emcguinnJune 18, 2020 Read More