Despite limited genomic diversity, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has shown a wide…
emcguinnSeptember 18, 2020
MHC Class II Transactivator CIITA Induces Cell Resistance to Ebola Virus and SARS-Like Coronaviruses
The authors have found a new pathway of cell resistance to viruses that is broad,…
Precise cell targeting is challenging because most mammalian cell types lack a single surface marker…
emcguinnSeptember 15, 2020
We recently showed that perineuronal nets (PNNs) enmesh glucoregulatory neurons in the arcuate nucleus (Arc)…
emcguinnSeptember 11, 2020
Rationale: Myocardial infarction (MI) causes spatial variation in collagen organization and phenotypic diversity in fibroblasts, which…
emcguinnSeptember 9, 2020
The recently emerged SARS-CoV-2 virus is currently causing a global pandemic and cases continue to…
emcguinnSeptember 4, 2020
In eukaryotes, conserved mechanisms ensure that cell growth is coordinated with nutrient availability. Overactive growth…
emcguinnSeptember 3, 2020
Proteins created from recurrent fusion genes like CBFB-MYH11 are prevalent in acute myeloid leukemia (AML), often necessary…
emcguinnAugust 27, 2020
We evaluate gene editing of HSV in a well-established mouse model, using adeno-associated virus (AAV)-delivered…
emcguinnAugust 25, 2020
The recently emerged SARS-CoV-2 virus is currently causing a global pandemic and cases continue to…
emcguinnAugust 24, 2020
