Publications of the Week

The human gene catalogue is essentially complete, but we lack an equivalently vetted inventory of…

Most infants with cystic fibrosis (CF) have pancreatic exocrine insufficiency that results in nutrient malabsorption…

Patients with cystic fibrosis (CF) have altered fecal microbiomes compared to those of healthy controls.…

It is known that capillaries in vivo are often blocked or obstructed in these diseases,…

Metabolic syndrome, including obesity and insulin resistance, compromises energy metabolism, mitochondrial function and heart performance.…

Deletions within genes coding for subunits of the transcription coactivator SAGA caused strong genome-wide defects…

Chimeric antigen receptor (CAR) T-cell therapy has produced remarkable anti-tumor responses in patients with B-cell…

Upon Ag exposure, naive B cells expressing BCR able to bind Ag can undergo robust…

Single agent checkpoint inhibitor therapy has not been effective for most gastrointestinal solid tumors, but…

Deciphering how signaling enzymes operate within discrete microenvironments is fundamental to understanding biological processes. A-kinase…