Publications of the Week Integrated Functional Genomic Analysis Enables Annotation of Kidney Genome-Wide Association Study LociSieber, K.B., et al. | February 25, 2019The Akilesh laboratory studies genome organization and function in the kidney. The kidney filter (glomerulus)…sciencecityFebruary 25, 2019 Read More
Publications of the Week An Antigenic Atlas of HIV-1 Escape from Broadly Neutralizing Antibodies Distinguishes Functional and Structural EpitopesDingens, A.S., et al. | February 21, 2019Anti-HIV broadly neutralizing antibodies (bnAbs) have revealed vaccine targets on the virus’s envelope (Env) protein…sciencecityFebruary 21, 2019 Read More
Publications of the Week Defining the Impact of Mutation Accumulation on Replicative Lifespan in Yeast Using Cancer-Associated Mutator PhenotypesLee, M.B., et al. | February 18, 2019Our lab in the Department of Pathology at UW is interested in how cells deal…sciencecityFebruary 18, 2019 Read More
Publications of the Week Development of Decreased-Gluten Wheat Enabled by Determination of the Genetic Basis of lys3a BarleyMoehs, C.P., et al. | February 15, 2019Celiac disease is the most common food-induced enteropathy in humans, with a prevalence of approximately…sciencecityFebruary 15, 2019 Read More
Publications of the Week Merkel Cell Polyomavirus Tumor Antigens Expressed in Merkel Cell Carcinoma Function Independently of the Ubiquitin Ligases Fbw7 and β-TrCPDye, K.N., et al. | February 13, 2019Merkel cell polyomavirus (MCPyV) accounts for 80% of all Merkel cell carcinoma (MCC) cases through…sciencecityFebruary 13, 2019 Read More
Publications of the Week Targeting the Perivascular Niche Sensitizes Disseminated Tumour Cells to ChemotherapyCarlson, P., et al. | February 8, 2019The presence of disseminated tumour cells (DTCs) in bone marrow is predictive of poor metastasis-free…sciencecityFebruary 8, 2019 Read More
Publications of the Week Characterizing the Major Structural Variant Alleles of the Human GenomeAudano, P.A., et al. | February 6, 2019In order to provide a comprehensive resource for human structural variants (SVs), we generated long-read…sciencecityFebruary 6, 2019 Read More
Publications of the Week Basophil-Derived Tumor Necrosis Factor Can Enhance Survival in a Sepsis Model in MiceScience in Seattle | February 4, 2019Our publication in Nature Immunology revealed how a rare group of white blood cells called basophils play…sciencecityFebruary 4, 2019 Read More
Publications of the Week CIRCling the Wagons to Protect Intestinal Stem CellsSoveg, F., et al. | February 1, 2019The epithelium of the small intestine is tasked with balancing its role of absorbing nutrients…sciencecityFebruary 1, 2019 Read More
Publications of the Week Chronic TLR7 and TLR9 Signaling Drives Anemia via Differentiation of Specialized HemophagocytesAkilesh, H.M., et al. | January 30, 2019Read the Publication This week we profile a recent publication in Science from Dr. Jessica…sciencecityJanuary 30, 2019 Read More