Publications of the Week Layer-by-Layer Functionalized Gauze With Designed α-Sheet Peptides Inhibits E. coli and S. aureus Biofilm Formation Nick, S., et al. | March 6, 2025 Microbial biofilms on wounds lead to longer hospital stays, mechanical debridement, and higher mortality. Amyloid…karnottMarch 6, 2025 Read More
Publications of the Week De Novo Designed Hsp70 Activator Dissolves Intracellular Condensates Zhang, J., et al. | February 26, 2025 Cells constantly use and recycle their proteins in a process called protein quality control (PQC).…karnottFebruary 26, 2025 Read More
Publications of the Week Metagenomic Estimation of Dietary Intake From Human Stool Diener, C., et al. | February 21, 2025 Dietary intake is tightly coupled to gut microbiota composition, human metabolism and the incidence of…karnottFebruary 21, 2025 Read More
Publications of the Week Multiplex Generation and Single-Cell Analysis of Structural Variants in Mammalian Genomes Pinglay, S., et al. | February 20, 2025 The structural variants (SVs) present in mammalian genomes include deletions, insertions, inversions, duplications, translocations, extrachromosomal…karnottFebruary 20, 2025 Read More
Publications of the Week APMAT Analysis Reveals the Association Between CD8 T Cell Receptors, Cognate Antigen, and T Cell Phenotype and Persistence Xie, J., et al. | February 12, 2025 Elucidating the relationships between a class I peptide antigen, a CD8 T cell receptor (TCR)…karnottFebruary 12, 2025 Read More
Publications of the Week Tissue-Resident Memory CD8 T Cell Diversity Is Spatiotemporally Imprinted Reina-Campos, M., et al. | February 5, 2025 This week, we profile a recent publication in Nature by Dr. Maximilian Heeg’s (pictured) lab…karnottFebruary 5, 2025 Read More
Publications of the Week A Novel Rapalog Shows Improved Safety vs. Efficacy in a Human Organoid Model of Polycystic Kidney Disease Gulieva, R., et al. | February 3, 2025 The mammalian target of rapamycin (mTOR) pathway is a therapeutic target in polycystic kidney disease…karnottFebruary 3, 2025 Read More
Publications of the Week De Novo Designed Proteins Neutralize Lethal Snake Venom Toxins Vázquez Torres, S., et al. | January 29, 2025 This week, we profile a recent publication in Nature by Dr. Susana Vázquez Torres (pictured) …karnottJanuary 29, 2025 Read More
Publications of the Week Characterization of Clonal Dynamics Using Duplex Sequencing in Donor-Recipient Pairs Decades After Hematopoietic Cell Transplantation Oshima, M., et al. | January 20, 2025 Donor-associated clonal hematopoiesis (CH) has been reported in recipients of allogeneic hematopoietic cell transplantation (HCT);…karnottJanuary 20, 2025 Read More
Publications of the Week Brain-Wide Cell-Type-Specific Transcriptomic Signatures of Healthy Ageing in Mice Jin, K., et al. | January 13, 2025 Biological ageing can be defined as a gradual loss of homeostasis across various aspects of…karnottJanuary 13, 2025 Read More