Publications of the Week Trimodal Single-Cell Profiling Reveals a Novel Pediatric CD8αα+ T Cell Subset and Broad Age-Related Molecular Reprogramming Across the T Cell CompartmentThomson, Z., et al. | October 19, 2023Age-associated changes in the T cell compartment are well described. However, limitations of current single-modal…sciencecityOctober 19, 2023 Read More
Publications of the Week Modulation of Influenza a Virus NS1 Expression Reveals Prioritization of Host Response Antagonism at Single-Cell ResolutionYang, Q., et al. | October 18, 2023Influenza A virus (IAV) is an important human respiratory pathogen that causes significant seasonal epidemics…sciencecityOctober 18, 2023 Read More
Publications of the Week Screening of Oligomeric (Meth)acrylate Vaccine Adjuvants Synthesized via Catalytic Chain Transfer PolymerizationHege, C., et al. | October 16, 2023This report details the first systematic screening of free-radical-produced methacrylate oligomer reaction mixtures as alternative…sciencecityOctober 16, 2023 Read More
Publications of the Week Epigenomic Analysis of Formalin-Fixed Paraffin-Embedded Samples by CUT&TagHenikoff, S., et al. | October 11, 2023For more than a century, formalin-fixed paraffin-embedded (FFPE) sample preparation has been the preferred method…sciencecityOctober 11, 2023 Read More
Publications of the Week Characteristics and Prognostic Impact of IDH Mutations in AML: A COG, SWOG, and ECOG AnalysisZarnegar-Lumley, S., et al. | October 9, 2023Somatic mutations in isocitrate dehydrogenase (IDH) genes occur frequently in adult acute myeloid leukemia (AML)…sciencecityOctober 9, 2023 Read More
Publications of the Week Donor Bone Marrow-Derived Macrophage Engraftment into the Central Nervous System of Patients Following Allogeneic TransplantationLoeb, A., et al. | October 6, 2023Hematopoietic stem cell transplantation is a well-known treatment for hematologic malignancies, wherein nascent stem cells…sciencecityOctober 6, 2023 Read More
Publications of the Week Neutralization, Effector Function and Immune Imprinting of Omicron VariantsAddetia, A., et al. | October 5, 2023Currently circulating SARS-CoV-2 variants have acquired convergent mutations at hot spots in the receptor-binding domain1 (RBD)…sciencecityOctober 5, 2023 Read More
Publications of the Week Breaching the Blood-Brain Barrier: AAV Triggers Dose-Dependent Toxicity in the Brain | September 29, 2023Since in vivo transduction of neurons and glia by adeno-associated virus (AAV) vectors was first…sciencecitySeptember 29, 2023 Read More
Publications of the Week Mesenchymal Stem Cell Extracellular Vesicles from Tissue-Mimetic System Enhance Epidermal Regeneration via Formation of Migratory Cell SheetsHodge, J., et al. | September 28, 2023The secretome of adipose-derived mesenchymal stem cells (ASCs) offers a unique approach to understanding and…sciencecitySeptember 28, 2023 Read More
Publications of the Week Non-mass Spectrometric Targeted Single-Cell MetabolomicsCheng, H., et al. | September 22, 2023Metabolic assays serve as pivotal tools in biomedical research, offering keen insights into cellular physiological…sciencecitySeptember 22, 2023 Read More