Publications of the Week

A major contributor to poor sensitivity to anti-cancer kinase inhibitor therapy is drug-induced cellular adaptation,…

Dravet syndrome (DS) is a severe and difficult-to-treat epileptic syndrome usually caused by a loss-of-function…

This multicenter, open-label, phase Ib study (ACE-LY-106) assessed the safety and efficacy of acalabrutinib, bendamustine,…

Cancer often exhibits genome-wide hypertranscription, but the mechanisms driving this phenomenon remain unclear. To understand…

Microbial biofilms on wounds lead to longer hospital stays, mechanical debridement, and higher mortality. Amyloid…

Cells constantly use and recycle their proteins in a process called protein quality control (PQC).…

Dietary intake is tightly coupled to gut microbiota composition, human metabolism and the incidence of…

The structural variants (SVs) present in mammalian genomes include deletions, insertions, inversions, duplications, translocations, extrachromosomal…

Elucidating the relationships between a class I peptide antigen, a CD8 T cell receptor (TCR)…

This week, we profile a recent publication in Nature by Dr. Maximilian Heeg’s (pictured) lab…