Publications of the Week Ferroptosis of Microglia in Aging Human White Matter InjuryAdeniyi, P., et al. | August 23, 2023Since the role of white matter degenerating microglia in myelination failure is unclear, we sought…sciencecityAugust 23, 2023 Read More
Publications of the Week DNA Repair Function Scores for 2172 Variants in the BRCA1 Amino-TerminusDiabate, M., et al. | August 22, 2023Single nucleotide variants are the most frequent type of sequence changes detected in the genome…sciencecityAugust 22, 2023 Read More
Publications of the Week Multi-Compartmental Analysis of the Murine Pulmonary Immune Response by Spectral Flow CytometryChang, M., et al. | August 22, 2023Studies of pulmonary inflammation require unique considerations due to the complex structure and composition of…sciencecityAugust 22, 2023 Read More
Publications of the Week MtrA Modulates Mycobacterium tuberculosis Cell Division in Host Microenvironments to Mediate Intrinsic Resistance and Drug TolerancePeterson, E., et al. | August 21, 2023Read the Publication This week we profile a recent publication in Cell Reports from the…sciencecityAugust 21, 2023 Read More
Publications of the Week Integrated Analysis of Cross-Links and Dead-End Peptides for Enhanced Interpretation of Quantitative XL-MSKeller, Andrew, et al. | August 16, 2023Chemical cross-linking with mass spectrometry provides low-resolution structural information on proteins in cells and tissues.…sciencecityAugust 16, 2023 Read More
Publications of the Week Familial Co-segregation and the Emerging Role of Long-Read Sequencing to Re-Classify Variants of Uncertain Significance in Inherited Retinal DiseasesGupta, P., et al. | August 15, 2023Phasing genetic variants is essential in determining those that are potentially disease-causing. In autosomal recessive…pthomsonAugust 15, 2023 Read More
Publications of the Week Peripheral Macrophages Drive CNS Disease in the Ndufs4(−/−) Model of Leigh SyndromeHanaford, Allison R., et al. | August 14, 2023Subacute necrotizing encephalopathy, or Leigh syndrome (LS), is the most common pediatric presentation of genetic…sciencecityAugust 14, 2023 Read More
Publications of the Week Observing Inhibition of the SARS-CoV-2 Helicase at Single-Nucleotide ResolutionLaszlo, A., et al. | August 11, 2023The genome of SARS-CoV-2 encodes for a helicase (nsp13) that is essential for viral replication…pthomsonAugust 11, 2023 Read More
Publications of the Week Proteogenomic Analysis of Chemo-Refractory High-Grade Serous Ovarian CancerPaulovich, A., et al. | August 7, 2023To improve the understanding of chemo-refractory high-grade serous ovarian cancers (HGSOCs), scientists characterized the proteogenomic…pthomsonAugust 7, 2023 Read More
Publications of the Week Donor T Cell STAT3 Deficiency Enables Tissue PD-L1–Dependent Prevention of Graft-Versus-Host Disease While Preserving Graft-Versus-Leukemia ActivityLi, Q., et al. | August 3, 2023STAT3 deficiency (STAT3–/–) in donor T cells prevents graft-versus-host disease (GVHD), but the impact on…pthomsonAugust 3, 2023 Read More