Publications of the Week Assessing Cytoskeletal Destruction During PyroptosisDavis, M.A. and Gale, M.J. | April 25, 2023Pyroptosis is an inflammatory form of cell death driven by the activation of caspase-1 and/or…sciencecityApril 25, 2023 Read More
Publications of the Week Amyloid Beta Peptides (Aβ) From Alzheimer’s Disease Neuronal Secretome Induce Endothelial Activation in a Human Cerebral Microvessel ModelShin, Y.J., et al. | April 21, 2023In Alzheimer's disease (AD), secretion and deposition of amyloid beta peptides (Aβ) have been associated…sciencecityApril 21, 2023 Read More
Publications of the Week Targeting Advanced Prostate Cancer With STEAP1 Chimeric Antigen Receptor T Cell and Tumor-Localized IL-12 ImmunotherapyBhatia, V., et al. | April 19, 2023Six transmembrane epithelial antigen of the prostate 1 (STEAP1) is a cell surface antigen for…sciencecityApril 19, 2023 Read More
Publications of the Week Evolution of the SARS-CoV-2 Mutational SpectrumBloom, J.D., et al. | April 14, 2023SARS-CoV-2 evolves rapidly in part because of its high mutation rate. Here we examine whether…sciencecityApril 14, 2023 Read More
Publications of the Week De Novo Design of Modular Peptide-Binding Proteins by Superhelical MatchingWu, K., et al. | April 12, 2023General approaches for designing sequence-specific peptide-binding proteins would have wide utility in proteomics and synthetic…sciencecityApril 12, 2023 Read More
Publications of the Week An Integrase Toolbox to Record Gene-Expression During Plant DevelopmentGuisiou, S., et al. | April 7, 2023There are many open questions about the mechanisms that coordinate the dynamic, multicellular behaviors required…sciencecityApril 7, 2023 Read More
Publications of the Week Structural Basis for Severe Pain Caused by Mutations in the S4-S5 Linkers of Voltage-Gated Sodium Channel Nav1.7Wisedchaisri, G., et al. | April 4, 2023Gain-of-function mutations in voltage-gated sodium channel NaV1.7 cause severe inherited pain syndromes, including inherited erythromelalgia…sciencecityApril 4, 2023 Read More
Publications of the Week Investigating Thymic Epithelial Cell Diversity Using Systems BiologyChiu, H., et al. | March 29, 2023The thymus is an intricate organ consisting of a diverse population of thymic epithelial cells…sciencecityMarch 29, 2023 Read More
Publications of the Week EXT418, a Novel Long-Acting Ghrelin, Mitigates Lewis Lung Carcinoma Induced Cachexia in MiceKerr, H.L., et al. | March 28, 2023 Ghrelin is a potential therapy for cachexia due to its orexigenic properties and anabolic effects…sciencecityMarch 28, 2023 Read More
Publications of the Week B Cell-Activating Factor (BAFF) From Dendritic Cells, Monocytes and Neutrophils Is Required for B Cell Maturation and Autoantibody Production in SLE-like Autoimmune DiseaseGiordano, D., et al. | March 22, 2023 B cell-activating factor (BAFF) contributes to the pathogenesis of autoimmune diseases including systemic lupus erythematosus…sciencecityMarch 22, 2023 Read More