Publications of the Week FLIP(C1orf112)-FIGNL1 Complex Regulates RAD51 Chromatin Association to Promote Viability After Replication Stress Tischler, J., et al. | January 30, 2024 Homologous recombination (HR) plays critical roles in repairing lesions that arise during DNA replication and…karnottJanuary 30, 2024 Read More
Publications of the Week DNA Methylation and Chromatin Accessibility Predict Age in the Domestic Dog Jin, K., et al. | January 25, 2024 Across mammals, the epigenome is highly predictive of chronological age. These "epigenetic clocks," most of…karnottJanuary 25, 2024 Read More
Publications of the Week Immune Evasion of Dormant Disseminated Tumor Cells Is Due to Their Scarcity and Can Be Overcome by T Cell Immunotherapies Goddard, E., et al. | January 16, 2024 The period between “successful” treatment of localized breast cancer and the onset of distant metastasis…karnottJanuary 16, 2024 Read More
Publications of the Week Assessing the Daily Natural History of Asymptomatic Plasmodium Infections in Adults and Older Children in Katakwi, Uganda: A Longitudinal Cohort Study Hergott, D., et al. | January 12, 2024 Low-density asymptomatic Plasmodium infections are prevalent in endemic areas, but little is known about their…karnottJanuary 12, 2024 Read More
Publications of the Week Cognitively Defined Alzheimer’s Dementia Subgroups Have Distinct Atrophy Patterns Crane, P., el al. | January 4, 2024 A personalized medicine approach has been recommended for Alzheimer's disease (AD).1, 2 One success story…karnottJanuary 4, 2024 Read More
Publications of the Week Zebrafish Cutaneous Injury Models Reveal That Langerhans Cells Engulf Axonal Debris in Adult Epidermis Peterman, E., et al. | January 2, 2024 Somatosensory neurons extend enormous peripheral axons to the skin, where they detect diverse environmental stimuli.…karnottJanuary 2, 2024 Read More
Publications of the Week Targeting the Fibroblast Growth Factor Pathway in Molecular Subtypes of Castration-Resistant Prostate Cancer Labrecque, M., et al. | December 14, 2023 Androgen receptor (AR) pathway inhibition remains the cornerstone for prostate cancer therapies. However, castration-resistant prostate…karnottDecember 14, 2023 Read More
Publications of the Week A First-in-Human, Open-Label Phase 1b and a Randomised, Double-Blind Phase 2a Clinical Trial in Recent-Onset Type 1 Diabetes with AG019 As Monotherapy and in Combination with Teplizumab Mathieu, C., et al. | December 13, 2023 We hypothesised that islet beta cell antigen presentation in the gut along with a tolerising…karnottDecember 13, 2023 Read More
Publications of the Week A Standard Workflow for Community-Driven Manual Curation of Strongyloides Genome Annotations Bryant, A., et al. | December 8, 2023 Advances in the functional genomics and bioinformatics toolkits for Strongyloides species have positioned these species as genetically…karnottDecember 8, 2023 Read More
Publications of the Week Expression of the Vesicular GABA Transporter within Neuromedin S+ Neurons Sustains Behavioral Circadian Rhythms Bussi, I.L., et al. | December 5, 2023 The suprachiasmatic nucleus (SCN) of the hypothalamus is the site of a central circadian clock…sciencecityDecember 5, 2023 Read More