Publications of the Week Information Flow in the Spatiotemporal Organization of Immune ResponsesHuang, J., Lyons-Cohen, M., and Gerner, M. | December 10, 2021Immune responses must be rapid, tightly orchestrated, and tailored to the encountered stimulus. Lymphatic vessels…dcorriganDecember 10, 2021 Read More
Publications of the Week Discrete Regulatory Modules Instruct Hematopoietic Lineage Commitment and DifferentiationGeorgolopoulos, G., et al. | December 9, 2021Lineage commitment and differentiation is driven by the concerted action of master transcriptional regulators at…dcorriganDecember 9, 2021 Read More
Publications of the Week Drug Delivery to the Central Nervous SystemNance, E., et al. | December 8, 2021Despite the rising global incidence of central nervous system (CNS) disorders, CNS drug development remains…dcorriganDecember 8, 2021 Read More
Publications of the Week Multiomic Characterization of Oncogenic Signaling Mediated by Wild-Type and Mutant RIT1Lo, A., et al. | December 3, 2021Aberrant activation of the RAS family of guanosine triphosphatases (GTPases) is prevalent in lung adenocarcinoma,…dcorriganDecember 3, 2021 Read More
Publications of the Week De Novo Protein Design by Deep Network HallucinationAnishchenko, I., et al. | December 2, 2021There has been considerable recent progress in protein structure prediction using deep neural networks to…dcorriganDecember 2, 2021 Read More
Publications of the Week Mucosal Tissue Regulatory T Cells Are Integral in Balancing Immunity and Tolerance at Portals of Antigen EntryTraxinger, B. R., Richert-Spuhler, L. E., and Lund, J. M. | December 1, 2021Foxp3+ regulatory T cells (Tregs) are a subset of CD4+ T cells that exert suppressive…dcorriganDecember 1, 2021 Read More
Publications of the Week Directional Reorientation of Migrating Neutrophils Is Limited by Suppression of Receptor Input Signaling at the Cell Rear through Myosin II ActivityHadjitheodorou, A., et al. | November 26, 2021To migrate efficiently to target locations, cells must integrate receptor inputs while maintaining polarity: a…dcorriganNovember 26, 2021 Read More
Publications of the Week Molecular Basis of Immune Evasion by the Delta and Kappa SARS-CoV-2 VariantsMccallum, M., et al. | November 25, 2021Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission leads to the emergence of variants, including…dcorriganNovember 25, 2021 Read More
Publications of the Week Cross-Validation of SARS-CoV-2 Responses in Kidney Organoids and Clinical PopulationsHelms, L., et al. | November 23, 2021Using organoids, the authors discovered that SARS-CoV-2 has an exquisite ability to infect a specific…dcorriganNovember 23, 2021 Read More
Publications of the Week An Invariant Protein That Co-Localizes with VAR2CSA on Plasmodium falciparum-Infected Red Cells Binds to Chondroitin Sulfate AKeitany, G., et al. | November 19, 2021Plasmodium falciparum-infected red blood cells (iRBCs) bind and sequester in deep vascular beds, causing malaria-related…dcorriganNovember 19, 2021 Read More