Publications of the Week Engineering a Niche Supporting Hematopoietic Stem Cell Development Using Integrated Single-Cell Transcriptomics Hadland, B., et al. | April 8, 2022 The authors used single-cell RNA-sequencing to simultaneously study the transcriptomes of newly forming embryonic hematopoietic…dcorriganApril 8, 2022 Read More
Publications of the Week Cutting Edge: Effect of Disease-Modifying Therapies on SARS-CoV-2 Vaccine–Induced Immune Responses in Multiple Sclerosis Patients Yuzefpolskiy, Y., et al. | April 6, 2022 Multiple sclerosis (MS) is a demyelinating inflammatory disease of the CNS treated by diverse disease-modifying…dcorriganApril 6, 2022 Read More
Publications of the Week A Phase I/II Trial Combining Avelumab and Trabectedin for Advanced Liposarcoma and Leiomyosarcoma Wagner, M. J., et al. | April 4, 2022 Leiomyosarcoma (LMS) and liposarcoma (LPS) frequently express PD-L1 but are generally resistant to PD-1/PD-L1 inhibition…dcorriganApril 4, 2022 Read More
Publications of the Week Effect of Lung Pericyte-Like Cell Ablation on the Bleomycin Model of Injury and Repair Hung, C., et al. | March 31, 2022 The authors have previously showed that pericyte-like cells derived from the FoxD1-lineage contribute to myofibroblasts…dcorriganMarch 31, 2022 Read More
Publications of the Week dCas9 Fusion to Computer-Designed PRC2 Inhibitor Reveals Functional TATA Box in Distal Promoter Region Levy, S., et al. | March 30, 2022 Bifurcation of cellular fates, a critical process in development, requires histone 3 lysine 27 methylation…dcorriganMarch 30, 2022 Read More
Publications of the Week Oral Desensitization Therapy for Peanut Allergy Induces Dynamic Changes in Peanut-Specific Immune Responses Bajzik, V., et al. | March 25, 2022 The authors defined key mechanistic correlates of the reduction of clinical reactivity to peanuts observed…dcorriganMarch 25, 2022 Read More
Publications of the Week The Endophilin Curvature-Sensitive Motif Requires Electrostatic Guidance to Recycle Synaptic Vesicles In Vivo Zhang, L., et al. | March 24, 2022 Curvature-sensing mechanisms assist proteins in executing particular actions on various membrane organelles. Here, we investigate…dcorriganMarch 24, 2022 Read More
Publications of the Week Lamin B1 Deletion in Myeloid Neoplasms Causes Nuclear Anomaly and Altered Hematopoietic Stem Cell Function Reilly, A., et al. | March 22, 2022 Abnormal nuclear morphology is a hallmark of most cancers, widely used in cancer diagnosis. In…dcorriganMarch 22, 2022 Read More
Publications of the Week The Alzheimer’s Gene SORL1 Is a Regulator of Endosomal Traffic and Recycling in Human Neurons Mishra, S., et al. | March 16, 2022 In this work, we continued our studies on the gene SORL1, which is emerging as…dcorriganMarch 16, 2022 Read More
Publications of the Week Mechanical Forces Govern Interactions of Host Cells with Intracellular Bacterial Pathogens Bastounis, E. E., et al. | March 16, 2022 To combat infectious diseases, it is important to understand how host cells interact with bacterial…dcorriganMarch 16, 2022 Read More