Publications of the Week Long-Read Human Genome Sequencing and Its ApplicationsLogsdon, G.A., et al. | June 12, 2020Over the past decade, long-read, single-molecule DNA sequencing technologies have emerged as powerful players in…eabramovichJune 12, 2020 Read More
Publications of the Week The 6–4 Photoproduct Is the Trigger of UV-Induced Replication Blockage and ATR ActivationHung, K.F., et al. | June 10, 2020UV radiation from the sun damages DNA and generates DNA ‘lesions’ which may become genetic…eabramovichJune 10, 2020 Read More
Publications of the Week Longitudinal Analysis Reveals Transition Barriers between Dominant Ecological States in the Gut MicrobiomeLevy, R., et al. | June 4, 2020Deep molecular phenotyping of individuals provides the opportunity for biological insight into host physiology. As…emcguinnJune 4, 2020 Read More
Publications of the Week Antibody and Cellular Responses to HIV Vaccine Regimens with DNA Plasmid as Compared with ALVAC Priming: An Analysis of Two Randomized Controlled TrialsMoodie, Z., et al. | June 3, 2020DNA plasmids promise a pragmatic alternative to viral vectors for prime-boost HIV-1 vaccines. We evaluated…emcguinnJune 3, 2020 Read More
Publications of the Week Reduced Oligodendrocyte Exosome Secretion in Multiple System Atrophy Involves SNARE DysfunctionYu, Z., et al. | May 29, 2020Transportation of key proteins via extracellular vesicles has been recently implicated in various neurodegenerative disorders,…emcguinnMay 29, 2020 Read More
Publications of the Week Robust Antibody and Cellular Responses Induced by DNA-Only Vaccination for HIVDeRosa, S., et al. | May 27, 2020HVTN 098, a randomized, double-blind, placebo-controlled trial, evaluated the safety, tolerability and immunogenicity of PENNVAX®-GP…emcguinnMay 27, 2020 Read More
Publications of the Week Intricate Genetic Programs Controlling Dormancy in Mycobacterium tuberculosisPeterson, E.J.R., et al. | May 19, 2020Mycobacterium tuberculosis (MTB) displays the remarkable ability to transition in and out of dormancy, a hallmark…eabramovichMay 19, 2020 Read More
Publications of the Week APOBEC3C Tandem Domain Proteins Create Super Restriction Factors against HIV-1McDonnell, M.M., et al. | May 18, 2020Humans encode proteins, called restriction factors, that inhibit replication of viruses such as HIV-1. The…eabramovichMay 18, 2020 Read More
Publications of the Week Allosteric Conformational Change of a Cyclic Nucleotide-Gated Ion Channel Revealed by DEER SpectroscopyStoll, S., et al. | May 14, 2020Using DEER in combination with electrophysiology, we were able to reveal a conformational change in…emcguinnMay 14, 2020 Read More
Publications of the Week Hybrid Insulin Peptides are Recognized by Human T Cells in the Context of DRB1*04:01James, E. A., et al. | May 7, 2020The overarching goal of our research is to develop an increasingly in- depth knowledge of…emcguinnMay 7, 2020 Read More