Publications of the Week A Lineage-Resolved Molecular Atlas of C. Elegans Embryogenesis at Single-Cell ResolutionPacker, J.S., et al. | September 27, 2019Single-cell RNA sequencing provides the power to identify the developmental trajectory of an organism. However,…sciencecitySeptember 27, 2019 Read More
Publications of the Week Tissue Chips in Space — Challenges and OpportunitiesYeung, C.K., et al. | September 25, 2019The microgravity environment results in a multitude of physiological changes associated with aging and altered…sciencecitySeptember 25, 2019 Read More
Publications of the Week Cell-Specific Image-Guided Transcriptomics Identifies Complex Injuries Caused by Ischemic Acute Kidney Injury in MiceMiyazaki, T., et al. | September 24, 2019The highly heterogeneous nature of the kidney’s tubular epithelium has made it challenging to identify…sciencecitySeptember 24, 2019 Read More
Publications of the Week Mechanisms of Interplay between Transcription Factors and the 3D GenomeKim, S. & Shendure, J. | September 20, 2019Transcription factors (TFs) bind DNA in a sequence-specific manner and thereby serve as the protein…sciencecitySeptember 20, 2019 Read More
Publications of the Week Innate Immunity Limits Protective Adaptive Immune Responses against Pre-Erythrocytic Malaria ParasitesMinkah, N.K., et al. | September 19, 2019The authors examined malaria vaccine efficacy in immunized mice in the presence or absence of…sciencecitySeptember 19, 2019 Read More
Publications of the Week A Pooled Single-Cell Genetic Screen Identifies Regulatory Checkpoints in the Continuum of the Epithelial-to-Mesenchymal TransitionMcFaline-Figueroa, J., et al. | September 17, 2019EMT is fundamental to normal development and has been implicated in disease as a mechanism…sciencecitySeptember 17, 2019 Read More
Publications of the Week Conserved Cell Types with Divergent Features in Human Versus Mouse CortexHodge, R.D., et al. | September 12, 2019Using single nucleus transcriptomics, the authors showed that there are many different molecularly distinct cell…sciencecitySeptember 12, 2019 Read More
Publications of the Week RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane IntegrityOrozco, S.L., et al. | September 10, 2019The authors have previously found that activation of "necroptosis" is accompanied by the production of…sciencecitySeptember 10, 2019 Read More
Publications of the Week Separate Polycomb Response Elements Control Chromatin State and Activation of the Vestigial GeneAhmad K., and Spens, A.E. | September 6, 2019Polycomb-based gene silencing is a central chromatin-based mechanism for shutting off genes during cell fate…sciencecitySeptember 6, 2019 Read More
Publications of the Week Discriminative T Cell Recognition of Cross-Reactive Islet-Antigens Is Associated with HLA-DQ8 Transdimer–Mediated Autoimmune DiabetesChow, I., et al. | September 3, 2019This publication made a key discovery about the structural and functional characteristics of T cells…sciencecitySeptember 3, 2019 Read More