Microglia maintain brain health and play important roles in disease and injury. Despite their known…
dcorriganAugust 19, 2021
Integrative Oncogene-Dependency Mapping Identifies RIT1 Vulnerabilities and Synergies in Lung Cancer
CRISPR-based cancer dependency maps are accelerating advances in cancer precision medicine, but adequate functional maps…
dcorriganAugust 12, 2021
3’3’-cyclic di-adenosine monophosphate (c-di-AMP) is an important nucleotide second messenger found throughout the bacterial domain…
dcorriganAugust 10, 2021
The lab focuses on analyzing cellular immune responses in the context of cancer and infectious…
dcorriganAugust 6, 2021
Neuroendocrine (NE) differentiation in metastatic castration-resistant prostate cancer (mCRPC) is an increasingly common clinical feature…
kchenAugust 2, 2021
IgG4-related disease (IgG4-RD) is a rare systemic fibroinflammatory disease frequently associated with allergy. The pathogenesis…
dcorriganJuly 29, 2021
Most actin-related proteins (Arps) are highly conserved and carry out well-defined cellular functions in eukaryotes.…
kchenJuly 28, 2021
Type 2 inflammation is associated with epithelial cell responses, including goblet cell hyperplasia, that promote…
kchenJuly 27, 2021
Neutrophils migrating through extravascular spaces must negotiate narrow matrix pores without losing directional movement. We…
kchenJuly 23, 2021
