Publications of the Week Longitudinally Stable T Cell Function and Innate Immune Activation Distinguish Healthy Adult Immunotypes Science Translational Medicine | June 9, 2025 Understanding immune system variation between and within individuals may offer insight into healthy aging and…karnottJune 9, 2025 Read More
Publications of the Week Decoding Post-Transcriptional Regulatory Networks by RNA-Linked CRISPR Screening in Human Cells Nugent, P., et al. | June 4, 2025 RNAs undergo a complex choreography of metabolic processes that are regulated by thousands of RNA-associated…karnottJune 4, 2025 Read More
Publications of the Week Myeloid Cell Genome-Wide Screen Identifies Variants Associated with Mycobacterium Tuberculosis-Induced Cytokine Transcriptional Responses Ivie, J.J., et al. | May 28, 2025 Immune and clinical outcomes to Mycobacterium tuberculosis (Mtb) infection vary greatly between individuals yet the…sciencecityMay 28, 2025 Read More
Publications of the Week Anti-HSP90α IgG May Protect Against Antiphospholipid Syndrome in Systemic Lupus Erythematosus by Reducing Platelet Activation Barguil Macêdo, M., et al. | May 26, 2025 Natural autoantibodies (NAAbs) are immunoglobulins generated in the absence of antigen provocation, with no inherent…sciencecityMay 26, 2025 Read More
Publications of the Week KAT5 Regulates Neurodevelopmental States Associated with G0-like Populations in Glioblastoma Mihalas, A.B., et al. | May 21, 2025 Quiescence cancer stem-like cells may play key roles in promoting tumor cell heterogeneity and recurrence…sciencecityMay 21, 2025 Read More
Publications of the Week Drosophila Epidermal Cells Are Intrinsically Mechanosensitive and Modulate Nociceptive Behavioral Outputs Yoshino, J., et al. | May 20, 2025 Somatosensory neurons (SSNs) that detect and transduce mechanical, thermal, and chemical stimuli densely innervate an…sciencecityMay 20, 2025 Read More
Publications of the Week In Vivo Functional Screens Reveal KEAP1 Loss as a Driver of Chemoresistance in Small Cell Lung Cancer Brumage, L., et al. | May 15, 2025 Exquisitely chemosensitive initially, small cell lung cancer (SCLC) exhibits dismal outcomes owing to rapid transition…karnottMay 15, 2025 Read More
Publications of the Week Enteric Tuft Cell Inflammasome Activation Drives NKp46+ILC3 IL22 via PGD2 and Inhibits Salmonella Churchill, M., et al. | May 14, 2025 To distinguish pathogens from commensals, the intestinal epithelium employs cytosolic innate immune sensors. Activation of…karnottMay 14, 2025 Read More
Publications of the Week Functional and Antigenic Landscape of the Nipah Virus Receptor-Binding Protein Larsen, B., et al. | May 7, 2025 Nipah virus recurrently spills over to humans, causing fatal infections. The viral receptor-binding protein (RBP…karnottMay 7, 2025 Read More
Publications of the Week In Vivo Functional Screens Reveal KEAP1 Loss as a Driver of Chemoresistance in Small Cell Lung Cancer Brumage, L., et al. | May 1, 2025 Exquisitely chemosensitive initially, small cell lung cancer (SCLC) exhibits dismal outcomes owing to rapid transition…karnottMay 1, 2025 Read More