Publications of the Week A Curious Case for Development of Kinase Inhibitors as Antigiardiasis Treatments Using Advanced Drug Techniques Michaels, S. A., et al. | February 19, 2021 In this manuscript we discuss emerging drug development tools that can be used to accelerate…emcguinnFebruary 19, 2021 Read More
Publications of the Week T Cells Specific for a Mycobacterial Glycolipid Expand after Intravenous Bacillus Calmette–Guérin Vaccination Layton, E. D., et al. | February 18, 2021 Peptide antigens are typically presented to T cells by highly polymorphic major histocompatibility complex (MHC)…emcguinnFebruary 18, 2021 Read More
Publications of the Week Residual β Cell Function in Long-Term Type 1 Diabetes Associates with Reduced Incidence of Hypoglycemia Gubitosi-Klug, R., et al. | February 12, 2021 We investigated residual β cell function in Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions…emcguinnFebruary 12, 2021 Read More
Publications of the Week Conformation-Dependent Blockage of Activated VWF Improves Outcomes of Traumatic Brain Injury in Mice Xu, X., et al. | February 9, 2021 Traumatic brain injury-induced coagulopathy (TBI-IC) causes life-threatening secondary intracranial bleeding. Its pathogenesis differs mechanistically from…emcguinnFebruary 9, 2021 Read More
Publications of the Week Rapid Adaptation to Human Protein Kinase R by a Unique Genomic Rearrangement in Rhesus Cytomegalovirus Child, S., et al. | February 4, 2021 Cytomegaloviruses (CMVs) are generally unable to cross species barriers, in part because prolonged coevolution with…emcguinnFebruary 4, 2021 Read More
Publications of the Week Pleiotropic Mutations Can Rapidly Evolve to Directly Benefit Self and Cooperative Partner Despite Unfavorable Conditions Hart, S., et al. | February 2, 2021 Cooperation, paying a cost to benefit others, is widespread. Cooperation can be promoted by pleiotropic…emcguinnFebruary 2, 2021 Read More
Publications of the Week Survey of Spiking in the Mouse Visual System Reveals Functional Hierarchy Siegle, J., et al. | January 27, 2021 The anatomy of the mammalian visual system, from the retina to the neocortex, is organized…emcguinnJanuary 27, 2021 Read More
Publications of the Week Prospective Mapping of Viral Mutations that Escape Antibodies Used to Treat COVID-19 Starr, T., et al. | January 26, 2021 Antibodies are a potential therapy for SARS-CoV-2, but the risk of the virus evolving to…emcguinnJanuary 26, 2021 Read More
Publications of the Week Photopatterned Biomolecule Immobilization to Guide Three-Dimensional Cell Fate in Natural Protein-Based Hydrogels Batalov, I., et al. | January 21, 2021 Hydrogel biomaterials derived from natural biopolymers (e.g., fibrin, collagen, decellularized extracellular matrix) are regularly utilized…emcguinnJanuary 21, 2021 Read More
Publications of the Week Thresholds for Post-Rebound SHIV Control after CCR5 Gene-Edited Autologous Hematopoietic Cell Transplantation Cardozo-Ojeda, E., et al. | January 19, 2021 Autologous, CCR5 gene-edited hematopoietic stem and progenitor cell (HSPC) transplantation is a promising strategy for…emcguinnJanuary 19, 2021 Read More