Publications of the Week Selective Androgen Receptor Modulators Activate the Canonical Prostate Cancer Androgen Receptor Program and Repress Cancer Growth Nyquist, D. M., et al. | May 28, 2021 Prostate cancer (PC) is driven by androgen receptor (AR) activity, a master regulator of prostate…kchenMay 28, 2021 Read More
Publications of the Week A Photoswitchable GPCR-Based Opsin for Presynaptic Inhibition Copits, A. B., et al. | May 26, 2021 The authors focus on neuromodulatory processing in the brain, as it relates to effective behavior.…kchenMay 26, 2021 Read More
Publications of the Week Enhancer Viruses for Combinatorial Cell-Subclass-Specific Labeling Daigle, L. T., et al. | May 20, 2021 The authors are developing adeno-associated viruses (AAVs) and transgenic tools to target and perturb a…kchenMay 20, 2021 Read More
Publications of the Week Tissue Context Determines the Penetrance of Regulatory DNA Variation Halow, M. J., et al. | May 19, 2021 Functional assessment of disease-associated sequence variation at non-coding regulatory elements is complicated by their high…kchenMay 19, 2021 Read More
Publications of the Week Structural Basis for Broad Coronavirus Neutralization Sauer, M. M., et al. | May 14, 2021 Three highly pathogenic β-coronaviruses have crossed the animal-to-human species barrier in the past two decades:…kchenMay 14, 2021 Read More
Publications of the Week Tumor-Associated Autoantibodies from Mouse Breast Cancer Models Are Found in Serum of Breast Cancer Patients Stanton, E., S. et al. | May 14, 2021 B cell responses to tumor antigens occur early in breast tumors and may identify immunogenic…kchenMay 14, 2021 Read More
Publications of the Week A High-Quality Bonobo Genome Refines the Analysis of Hominid Evolution Mao Y., et al. | May 7, 2021 The divergence of chimpanzee and bonobo provides one of the few examples of recent hominid…kchenMay 7, 2021 Read More
Publications of the Week Identification of In Vivo Hox13 Binding Sites Reveals an Essential Locus Controlling Zebrafish Brachyury Expression Ye. Z., et al. | May 3, 2021 During early embryogenesis the vertebrate embryo extends from anterior to posterior due to the progressive…kchenMay 3, 2021 Read More
Publications of the Week Mediator Subunit Med15 Dictates the Conserved “Fuzzy” Binding Mechanism of Yeast Transcription Activators Gal4 and Gcn4 Tuttle, M. T., et al. | April 28, 2021 The focus of my lab is on mechanisms of transcriptional regulation. We use the yeast…kchenApril 28, 2021 Read More
Publications of the Week Functional Enhancer Elements Drive Subclass-Selective Expression from Mouse to Primate Neocortex Mich, K. J., et al. | April 27, 2021 The authors show that we can target expression from our AAV vectors in distinct brain…kchenApril 27, 2021 Read More