Publications of the Week Structure, Subunit Organization and Behavior of the Asymmetric Type IIT Restriction Endonuclease BbvCIShen, B.W., et al. | November 27, 2018BbvCI, a Type IIT restriction endonuclease, recognizes and cleaves the seven base pair sequence 5'-CCTCAGC-3',…sciencecityNovember 27, 2018 Read More
Publications of the Week A Bifunctional Role for the UHRF1 UBL Domain in the Control of Hemi-Methylated DNA-Dependent Histone UbiquitylationDaRosa, P.A., et al. | November 23, 2018This publication reports on the structural mechanism by methylated CpG motifs are maintained following DNA…sciencecityNovember 23, 2018 Read More
Publications of the Week Oncogenic Activation of PI3K Induces Progenitor Cell Differentiation to Suppress Epidermal GrowthZhe, Y., et al. | November 21, 2018Our recent work discovered stem cell differentiation as the primary block to oncogene-driven clonal expansion…sciencecityNovember 21, 2018 Read More
Publications of the Week h-Channels Contribute to Divergent Intrinsic Membrane Properties of Supragranular Pyramidal Neurons in Human Versus Mouse Cerebral CortexKalmbach, B.E., et al. | November 19, 2018Human and rodent brains are clearly different in terms of size and complexity. Yet, how…sciencecityNovember 19, 2018 Read More
Publications of the Week Dormant Tumor Cells, Their Niches and the Influence of ImmunityGoddard, E.T., et al. | November 15, 2018Despite increased focus on the clinical relevance of dormant metastatic disease, our understanding of dormant…sciencecityNovember 15, 2018 Read More
Publications of the Week De Novo Design of a Non-Local β-Sheet Protein with High Stability and AccuracyMarcos, E., et al. | November 13, 2018Natural proteins evolved over billions of years to solve biology’s most complex problems. But we…sciencecityNovember 13, 2018 Read More
Publications of the Week Parabrachial CGRP Neurons Establish and Sustain Aversive Taste MemoriesChen, J.Y., et al. | November 9, 2018Food aversions develop when the taste of a novel food is associated with sickness, which…sciencecityNovember 9, 2018 Read More
Publications of the Week A Biobank of Patient-Derived Pediatric Brain Tumor ModelsBrabetz, S., et al. | November 5, 2018Our team focuses on pediatric brain tumor therapeutics and the discovery of novel peptide therapeutics…sciencecityNovember 5, 2018 Read More
Publications of the Week Automated Quantification of Bioluminescence ImagesKlose, A.D. and Paragas, N. | November 2, 2018We developed a computer-aided analysis tool for quantitatively determining bioluminescent reporter distributions inside small animals.…sciencecityNovember 2, 2018 Read More
Publications of the Week Therapeutic Strategies Targeting ConnexinsLaird, D.W. and Lampe, P.D. | October 31, 2018The connexin family of channel-forming proteins is present in every tissue type in the human…sciencecityOctober 31, 2018 Read More