Publications of the Week Transcriptional Fates of Human-Specific Segmental Duplications in BrainDougherty, M.L., et al. | October 5, 2018Despite the importance of duplicate genes for evolutionary adaptation, accurate gene annotation is often incomplete,…sciencecityOctober 5, 2018 Read More
Publications of the Week Label-Free Prediction of Three-Dimensional Fluorescence Images from Transmitted-Light MicroscopyOunkomol, C., et al. | October 1, 2018The mission of the Allen Institute for Cell Science is to create dynamic and multi-scale…sciencecityOctober 1, 2018 Read More
Publications of the Week A Plant-Responsive Bacterial-Signaling System Senses an Ethanolamine DerivativeCoutinho, B.G., et la. | September 28, 2018The research in the Greenberg laboratory focuses on the emerging field of sociomicrobiology – the…sciencecitySeptember 28, 2018 Read More
Publications of the Week Aligning Single-Cell Developmental and Reprogramming Trajectories Identifies Molecular Determinants of Myogenic Reprogramming OutcomeCacchiarelli, D., et al. | September 27, 2018Cellular reprogramming through manipulation of defined factors holds great promise for large-scale production of cell…sciencecitySeptember 27, 2018 Read More
Publications of the Week Activated PIK3CD Drives Innate B Cell Expansion yet Limits B Cell-Intrinsic Immune ResponsesWray-Dutra, M.N., et al. | September 24, 2018Activated PI3K-delta syndrome (APDS) is an immunodeficiency caused by gain-of-function mutations in PIK3CD. This disease…sciencecitySeptember 24, 2018 Read More
Publications of the Week Receptive Field Center-Surround Interactions Mediate Context-Dependent Spatial Contrast Encoding in the RetinaTurner, M.H., et al. | September 20, 2018Antagonistic receptive field surrounds are a near-universal property of early sensory processing. A key assumption…sciencecitySeptember 20, 2018 Read More
Publications of the Week Chemical Cross-Linking with Mass Spectrometry: A Tool for Systems Structural BiologyChavez, J.D. and Bruce, J.E. | September 18, 2018Biological processes supporting life are orchestrated by a highly dynamic array of protein structures and…sciencecitySeptember 18, 2018 Read More
Publications of the Week Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate DisseminationCohen, S.B., et al. | September 14, 2018Mycobacterium tuberculosis (Mtb) infection is initiated in the distal airways, but the bacteria ultimately disseminate to…sciencecitySeptember 14, 2018 Read More
Publications of the Week Human T Cell Receptor Occurrence Patterns Encode Immune History, Genetic Background, and Receptor SpecificityDeWitt, W.S., et al. | September 10, 2018High-throughput DNA sequencing has enabled deep profiling of the set of receptors that T and…sciencecitySeptember 10, 2018 Read More
Publications of the Week Cas9 Immunity Creates Challenges for CRISPR Gene Editing TherapiesCrudele, J.M., et al. | September 5, 2018Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 is a genome-editing technology1,2 that utilizes archaeal and bacterial…sciencecitySeptember 5, 2018 Read More