Publications of the Week Reprogramming Identifies Functionally Distinct Stages of Clonal Evolution in Myelodysplastic Syndromes Hsu, J., et al. | July 24, 2019 The authors show that episomal reprogramming of MDS and AML patient samples to iPSCs captures…sciencecityJuly 24, 2019 Read More
Publications of the Week Controlling Protein Assembly on Inorganic Crystals through Designed Protein Interfaces Pyles, H., et al. | July 22, 2019 Many hard biomaterials like bone and teeth get their exquisite material properties from protein–mineral interactions.…sciencecityJuly 22, 2019 Read More
Publications of the Week Human 5′ UTR Design and Variant Effect Prediction from a Massively Parallel Translation Assay Sample, P.J., et al. | July 19, 2019 There are two main applications for this work. First, the scientists can use their models…sciencecityJuly 19, 2019 Read More
Publications of the Week Genetic Variation, Comparative Genomics, and the Diagnosis of Disease Evan Eichler | July 17, 2019 The genome is not akin to a string of fixed length. Many large segments of…sciencecityJuly 17, 2019 Read More
Publications of the Week Pandemic Fluoroquinolone Resistant Escherichia coli Clone ST1193 Emerged via Simultaneous Homologous Recombinations in 11 Gene Loci Tchesnokova, V., et al. | July 15, 2019 This research shows that pandemic multi-drug resistant (‘superbug’) strains can emerge virtually instantly, without a…sciencecityJuly 15, 2019 Read More
Publications of the Week Fasting Prevents Hypoxia-Induced Defects of Proteostasis in C. Elegans Iranon, N.N., et al. | July 10, 2019 Low oxygen conditions (hypoxia) can impair essential physiological processes and cause cellular damage and death.…sciencecityJuly 10, 2019 Read More
Publications of the Week Interferon-λ Modulates Dendritic Cells to Facilitate T Cell Immunity during Infection with Influenza a Virus Hemann, E.A., et al. | July 8, 2019 Type III interferon (IFN-λ) is important for innate immune protection at mucosal surfaces and has…sciencecityJuly 8, 2019 Read More
Publications of the Week T Cell Receptor Gene Therapy Targeting WT1 Prevents Acute Myeloid Leukemia Relapse Post-Transplant Chapuis, A.G., et al. | July 5, 2019 Relapse after allogeneic hematopoietic cell transplantation (HCT) is the leading cause of death in patients…sciencecityJuly 5, 2019 Read More
Publications of the Week Classification of Electrophysiological and Morphological Neuron Types in the Mouse Visual Cortex Gouwens, N.W., et al. | July 1, 2019 Understanding the diversity of cell types in the brain has been an enduring challenge and…sciencecityJuly 1, 2019 Read More
Publications of the Week Intratumoral Activation of the Necroptotic Pathway Components RIPK1 and RIPK3 Potentiates Antitumor Immunity Snyder, A.G., et al. | June 28, 2019 Although the signaling events that induce different forms of programmed cell death are well defined,…sciencecityJune 28, 2019 Read More