Publications of the Week Genetic and Epigenetic Screens in Primary Human T Cells Link Candidate Causal Autoimmune Variants to T Cell Networks Ho, C., et al. | September 25, 2025 Genetic variants associated with autoimmune diseases are highly enriched within putative cis-regulatory regions of CD4+…karnottSeptember 25, 2025 Read More
Publications of the Week Preventing Hypocontractility-Induced Fibroblast Expansion Alleviates Dilated Cardiomyopathy Bretherton, R., et al. | September 16, 2025 Cardiomyocyte hypocontractility underlies inherited dilated cardiomyopathy (DCM). Yet, whether fibroblasts modify DCM phenotypes remains unclear…karnottSeptember 16, 2025 Read More
Publications of the Week Early and Opposing Neutrophil and CD4 T Cell Responses Shape Pulmonary Tuberculosis Pathology Gern, B., et al. | September 10, 2025 Pulmonary Mycobacterium tuberculosis (Mtb) infection results in a variety of heterogeneous lesion structures, from necrotic…karnottSeptember 10, 2025 Read More
Publications of the Week PhoCoil: A Photodegradable and Injectable Single-Component Recombinant Protein Hydrogel for Minimally Invasive Delivery and Degradation Gregorio, N., et al. | September 4, 2025 Hydrogel biomaterials offer great promise for three-dimensional cell culture and therapeutic delivery. Despite many successes,…karnottSeptember 4, 2025 Read More
Publications of the Week Genetically Encoded Interpenetrating Polymer Networks As Injectable Biomaterials for Controlled Therapeutic Protein Delivery Ross, M., et al. | August 25, 2025 Though recombinant protein therapeutics hold great potential in treating many diseases, their intravenous delivery introduces…karnottAugust 25, 2025 Read More
Publications of the Week Dendritic atoh1a+ Cells Serve As Merkel Cell Precursors During Skin Development and Regeneration Craig, E., et al. | August 20, 2025 Sensory cells often adopt specific morphologies that aid in the detection of external stimuli. Merkel…karnottAugust 20, 2025 Read More
Publications of the Week Metagenomic Estimation of Absolute Bacterial Biomass in the Mammalian Gut Through Host-Derived Read Normalization Tang, G., et al. | August 18, 2025 Absolute bacterial biomass estimation in the human gut is crucial for understanding microbiome dynamics and…karnottAugust 18, 2025 Read More
Publications of the Week Decoding Post-Transcriptional Regulatory Networks by RNA-Linked CRISPR Screening in Human Cells Nugent, P., et al. | August 11, 2025 RNAs undergo a complex choreography of metabolic processes that are regulated by thousands of RNA-associated…karnottAugust 11, 2025 Read More
Publications of the Week Design of Intrinsically Disordered Region Binding Proteins Wu, K., et al. | August 4, 2025 Intrinsically disordered proteins and protein domains have sequences that lack three-dimensional structure, but these proteins…karnottAugust 4, 2025 Read More
Publications of the Week Humoral Determinants of Checkpoint Immunotherapy Dai, Y., et al. | July 31, 2025 Although the role of cellular immunity in checkpoint immunotherapy (CPI) for cancer is well established1,2,…karnottJuly 31, 2025 Read More