Publications of the Week Inflammatory Pathways in Residual Asthma Exacerbations Among Mepolizumab-Treated Urban Children Altman, M., et al. | July 21, 2025 What molecular mechanisms underlie acute exacerbations in children with asthma treated with biologic therapies, where…karnottJuly 21, 2025 Read More
Publications of the Week Intranasal Replicon SARS-CoV-2 Vaccine Produces Protective Respiratory and Systemic Immunity and Prevents Viral Transmission Jennewein, M., et al. | July 15, 2025 While mRNA vaccines have been effective in combating SARS-CoV-2, the waning of vaccine-induced antibody responses…karnottJuly 15, 2025 Read More
Publications of the Week Drp1 Knockdown Aggravates Obesity-Induced Cardiac Dysfunction and Remodeling Wu, D., et al. | July 14, 2025 Obesity is an independent risk factor for heart failure with preserved ejection fraction (HFpEF). Dynamin…karnottJuly 14, 2025 Read More
Publications of the Week The Alzheimer’s Disease Gene SORL1 Regulates Lysosome Function in Human Microglia Mishra, S., et al. | July 11, 2025 The SORL1 gene encodes the sortilin-related receptor protein SORLA, a sorting receptor that regulates endo-lysosomal…karnottJuly 11, 2025 Read More
Publications of the Week Molecular Profiling of Adult C. elegans Glia Across Sexes by Single-Nuclear RNA-Seq Purice, M., et al. | July 7, 2025 A comprehensive understanding of nervous system function requires molecular insight into the diversity and sex…karnottJuly 7, 2025 Read More
Publications of the Week Elicitation of Liver-Stage Immunity by Nanoparticle Immunogens Displaying P. falciparum CSP-Derived Antigens Langowski, M., et al. | July 2, 2025 A vaccine that provides robust, durable protection against malaria remains a global health priority. Although…karnottJuly 2, 2025 Read More
Publications of the Week Anti-Sporozoite Monoclonal Antibody for Malaria Prevention: Secondary Efficacy Outcome of a Phase 2 Randomized Trial Skinner, J., et al. | June 24, 2025 CIS43LS is a long-acting monoclonal antibody specific for the Plasmodium falciparum circumsporozoite protein expressed on…karnottJune 24, 2025 Read More
Publications of the Week Emergence and Disruption of Cooperativity in a Denitrifying Microbial Community Carr, A., et al. | June 23, 2025 Anthropogenic perturbations to the nitrogen cycle, primarily through use of synthetic fertilizers, is driving an…karnottJune 23, 2025 Read More
Publications of the Week Enhancer AAVs for Targeting Spinal Motor Neurons and Descending Motor Pathways in Rodents and Macaque Kussick, E., et al. | June 20, 2025 Experimental access to cell types within the mammalian spinal cord is severely limited by the…karnottJune 20, 2025 Read More
Publications of the Week Human De Novo Mutation Rates From a Four-Generation Pedigree Reference Porubsky, D., et al. | June 19, 2025 Understanding the human de novo mutation (DNM) rate requires complete sequence information1. Here using five…karnottJune 19, 2025 Read More